3-Bromo-5-iodopyridine

Basic Information

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CAS Number

233770-01-9

Molecular Formula

C5H3BrIN

Molecular Weight

283.89 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

131.0 to 135.0 deg-C

Boiling Point

266.5℃ at 760 mmHg

Water Solubility

Slightly soluble in water.

SMILES

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C1=C(C=NC=C1I)Br

InChI

InChI=1S/C5H3BrIN/c6-4-1-5(7)3-8-2-4/h1-3H

InChIKey

AOOZLVWDZUPEHT-UHFFFAOYSA-N

LogP

2.4487000000000005

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

78.8

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H318 Causes serious eye damage
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Light Sensitive

Synonyms & References

English

J-512025
233770-01-9
MFCD03086019
AOOZLVWDZUPEHT-UHFFFAOYSA-N
AC-6899
SCHEMBL320374
DTXSID50356206
AO-801/41077497
Pyridine, 3-bromo-5-iodo-
CS-W007831
SY031472
3-Bromo-5-iodopyridine;Pyridine, 3-bromo-5-iodo-
BS-2044
3-bromo-5-iodopyridine
3-Bromo-5-iodopyridine, 95%
BCP22125
A4909
AM62380
B4346
SS-6056
AKOS005255449
Z1269188472
3-Bromo-5-iodo-pyridine
EN300-202965
AB13102
FT-0649699
3-Bromo-5-iodopyridine
3-BROMO-5-IODO-PYRIDINE
5-BROMO-3-IODOPYRIDINE
C5H3BrIN
3-?Bromo-?5-?iodopyridine

MDL Number

MFCD03086019

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 3-Bromo-5-iodopyridine (CAS: 233770-01-9)?

3-Bromo-5-iodopyridine (CAS: 233770-01-9) is a crystalline solid with a molecular weight of approximately 327.04 g/mol. It is poorly soluble in water but soluble in organic solvents like ethanol and acetone. The compound is known for its high reactivity due to the presence of both a bromine and an iodine substituent, which can undergo various reactions such as substitution and nucleophilic aromatic substitution.

How is 3-Bromo-5-iodopyridine (CAS: 233770-01-9) typically synthesized?

3-Bromo-5-iodopyridine (CAS: 233770-01-9) can be synthesized via a multi-step process involving the Brignac reaction. Initially, pyridine is brominated followed by iodination. Commonly used catalysts include silver salts and n-butyllithium. The overall yield is moderate, and selectivity for the iodination step is typically high.

What industries use 3-Bromo-5-iodopyridine (CAS: 233770-01-9)?

3-Bromo-5-iodopyridine (CAS: 233770-01-9) finds applications in pharmaceuticals, where it serves as a precursor for the synthesis of certain drugs. It is also used in the development of sensor technologies and as a building block in the production of certain organic semiconductors. Additionally, it plays a role in polymer chemistry for the synthesis of novel materials with specific properties.

What precautions should be taken when handling 3-Bromo-5-iodopyridine (CAS: 233770-01-9)?

When handling 3-Bromo-5-iodopyridine (CAS: 233770-01-9), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area, preferably in a fume hood. Spills should be cleaned up using appropriate chemicals, and the area should be thoroughly rinsed. Always consult the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.