(2,6-Dimethoxyphenyl)boronic acid

Basic Information

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CAS Number

23112-96-1

Molecular Formula

C8H11BO4

Molecular Weight

181.98 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Melting Point

110-112 °C

Boiling Point

372.8°C at 760 mmHg

Density

1.1900

Flash Point

179.3℃

SMILES

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B(C1=C(C=CC=C1OC)OC)(O)O

InChI

InChI=1S/C8H11BO4/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5,10-11H,1-2H3

InChIKey

BKWVXPCYDRURMK-UHFFFAOYSA-N

LogP

-0.6164000000000002

Topological Polar Surface Area

58.92 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

141

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

23112-96-1
AKOS002663425
AF-399/25108058
(2,6-dimethoxyphenyl)boronic acid
CS-W019869
NCGC00249518-01
2,6-DIMETHOXYPHENYL-BORONIC ACID
AC-24791
Z1203159460
D3861
AM86786
SCHEMBL203282
A4891
Boronic acid, (2,6-dimethoxyphenyl)-
2,6-Dimethoxybenzeneboronic Acid
EN300-119838
2,6-dimethoxybenzene boronic acid
BCP19585
B-(2,6-Dimethoxy-phenyl)boronic acid
FT-0638295
2,6-dimethoxy-phenylboronic acid
2,6-Dimethoxyphenylboronicacid
MFCD01318987
BP-12137
Boronic acid, B-(2,6-dimethoxyphenyl)-
DTXSID40370234
BKWVXPCYDRURMK-UHFFFAOYSA-N
AB08798
GS-6777
(2,6-dimethoxy)phenylboronic acid
J-507496

MDL Number

MFCD01318987

Customs Code

29319090

FAQ

What are the physical and chemical properties of (2,6-Dimethoxyphenyl)boronic acid (CAS: 23112-96-1)?

(2,6-Dimethoxyphenyl)boronic acid is a white crystalline solid with a molecular weight of approximately 232.24 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and dichloromethane. The compound exhibits typical reactivity of boronic acids, such as participation in Suzuki-Miyaura cross-coupling reactions. It is stable under normal conditions but should be stored in a cool, dry place away from strong acids and bases.

How is (2,6-Dimethoxyphenyl)boronic acid (CAS: 23112-96-1) typically synthesized?

(2,6-Dimethoxyphenyl)boronic acid is commonly synthesized via the boronation of 2,6-dimethoxybenzene using a boronate ester such as phenylboronic acid as a starting material. The reaction typically involves the use of a base like triphenylphosphine in the presence of a catalyst like palladium(II) acetate. The yield is usually high, and the process is highly selective, making it a reliable method for producing this compound.

What industries use (2,6-Dimethoxyphenyl)boronic acid (CAS: 23112-96-1)?

(2,6-Dimethoxyphenyl)boronic acid finds applications in various industries, particularly in the pharmaceutical sector for its use as a key intermediate in the synthesis of bioactive compounds. It is also used in the polymer industry for modifying the properties of polymers, in the sensor industry for developing sensitive detection devices, and in semiconductor manufacturing for its role in thin film deposition processes.

What precautions should be taken when handling (2,6-Dimethoxyphenyl)boronic acid (CAS: 23112-96-1)?

When handling (2,6-Dimethoxyphenyl)boronic acid, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be stored in a fume hood to avoid inhalation risks and to minimize exposure to air. Spills should be cleaned up immediately using appropriate cleanup materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.