5-Amino-2-methyl-1H-isoindole-1,3(2H)-dione

Basic Information

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CAS Number

2307-00-8

Molecular Formula

C9H8N2O2

Molecular Weight

176.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Powder

Melting Point

246-248 °C

Boiling Point

368.3°C at 760 mmHg

Density

1.411

Flash Point

176.6°C

SMILES

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CN1C(=O)C2=C(C1=O)C=C(C=C2)N

InChI

InChI=1S/C9H8N2O2/c1-11-8(12)6-3-2-5(10)4-7(6)9(11)13/h2-4H,10H2,1H3

InChIKey

KMEBUNSLFRQSEM-UHFFFAOYSA-N

LogP

0.49460000000000015

Topological Polar Surface Area

63.4 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

264

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

5-Amino-2-methylisoindoline-1,3-dione
EN300-02523
Oprea1_420392
D82239
1H-Isoindole-1,3(2H)-dione, 5-amino-2-methyl-
MFCD00012081
KMEBUNSLFRQSEM-UHFFFAOYSA-N
5-amino-2-methylisoindole-1,3-dione
HMS1789H16
4-Amino-N-methylphthalimide, 97%
4-Amino-N-methylphthalimide
BB 0246023
AS-17371
5-amino-2-methyl-2,3-dihydro-1H-isoindole-1,3-dione
J-014974
F1386-0358
FT-0617590
5-amino-2-methyl-1H-isoindole-1,3(2H)-dione
BDBM625946
AC-24980
AKOS000111092
SY036429
5-amino-2-methyl-isoindole-1,3-dione
CS-0076926
A816552
SB66132
1H-Isoindole-1,3(2H)-dione,4-amino-2-methyl-
5-azanyl-2-methyl-isoindole-1,3-dione
CCG-54996
4-Amino-N-methyl-phthalimid
Z57036341

MDL Number

MFCD00012081

Customs Code

2925190090

FAQ

What are the physical and chemical properties of 5-Amino-2-methyl-1H-isoindole-1,3(2H)-dione (CAS: 2307-00-8)?

5-Amino-2-methyl-1H-isoindole-1,3(2H)-dione (CAS: 2307-00-8) is a white crystalline solid with a molecular weight of approximately 208.23 g/mol. It has a solubility of about 10 mg/mL in water and is slightly soluble in ethanol. This compound is known for its low reactivity under normal conditions but can undergo substitution reactions under certain conditions.

How is 5-Amino-2-methyl-1H-isoindole-1,3(2H)-dione (CAS: 2307-00-8) typically synthesized?

5-Amino-2-methyl-1H-isoindole-1,3(2H)-dione (CAS: 2307-00-8) can be synthesized through either a condensation reaction of 2-methyl-1H-isoindole-1-carboxylic acid with an amine or through a direct synthesis of the amine and the acid. Commonly used catalysts include tetrabutylammonium hexafluorophosphate, and the process yields up to 85% of the desired product.

What industries use 5-Amino-2-methyl-1H-isoindole-1,3(2H)-dione (CAS: 2307-00-8)?

5-Amino-2-methyl-1H-isoindole-1,3(2H)-dione (CAS: 2307-00-8) is primarily used in pharmaceuticals for its potential as a precursor in the synthesis of various drugs. It is also utilized in the development of sensors and in the production of certain polymers due to its chemical reactivity and stability.

What precautions should be taken when handling 5-Amino-2-methyl-1H-isoindole-1,3(2H)-dione (CAS: 2307-00-8)?

When handling 5-Amino-2-methyl-1H-isoindole-1,3(2H)-dione (CAS: 2307-00-8), ensure appropriate personal protective equipment (PPE) is used, including gloves and safety goggles. It should be handled in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be cleaned up carefully, and the material safety data sheet (MSDS) should be consulted for specific spill procedures.