Compound Q&A

How is 5-Amino-2-methyl-1H-isoindole-1,3(2H)-dione (CAS: 2307-00-8) typically synthesized?

Answer

5-Amino-2-methyl-1H-isoindole-1,3(2H)-dione
5-Amino-2-methyl-1H-isoindole-1,3(2H)-dione (CAS: 2307-00-8) can be synthesized through either a condensation reaction of 2-methyl-1H-isoindole-1-carboxylic acid with an amine or through a direct synthesis of the amine and the acid. Commonly used catalysts include tetrabutylammonium hexafluorophosphate, and the process yields up to 85% of the desired product.

About

CAS No 2307-00-8
English Name 5-Amino-2-methyl-1H-isoindole-1,3(2H)-dione
Molecular Formula C9H8N2O2
Molecular Weight 176.17 g/mol
SMILES CN1C(=O)C2=C(C1=O)C=C(C=C2)N
InChIKey KMEBUNSLFRQSEM-UHFFFAOYSA-N
Last Updated: 2025-09-10 15:15

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