4-Dodecanolide

Basic Information

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CAS Number

2305-05-7

Molecular Formula

C12H22O2

Molecular Weight

198.31 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

17-18 °C

Boiling Point

130-132 °C/1.5 mmHg

Refractive Index

n20/D 1.451-1.453<br />n20/D 1.452(lit.)

SMILES

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CCCCCCCCC1CCC(=O)O1

InChI

InChI=1S/C12H22O2/c1-2-3-4-5-6-7-8-11-9-10-12(13)14-11/h11H,2-10H2,1H3

InChIKey

WGPCZPLRVAWXPW-UHFFFAOYSA-N

LogP

3.4426000000000023

Topological Polar Surface Area

26.3 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

166

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

dihydro-5-octylfuran-2(3H)-one
Gamma-Dodecalactone
gamma-Octyl-gamma-butyrolactone
Dihydro-5-octyl-2(3H)-furanone
4-Dodecanolide
GAMMA-DODECANOLACTONE
γ-Dodecalactone
(±)-Dihydro-5-octyl-2(3H)-furanone
(±)-γ-Octyl-γ-butyrolactone
dodecalactone
Dodecanolide-1,4
DODECANYL-LACTONE
FEMA 2400
G-DODECALACTONE
g-Dodecanolactone
γ-Dodecanolactone
γ-Laurolactone

MDL Number

MFCD00036499

Customs Code

2932209090

FAQ

What are the physical and chemical properties of 4-Dodecanolide (CAS: 2305-05-7)?

4-Dodecanolide (CAS: 2305-05-7) is a colorless or light yellow crystalline compound with a molecular weight of approximately 246.36 g/mol. It has a solubility of about 1.2 g/L in water at 25°C. The compound is relatively stable under normal conditions but undergoes hydrolysis when exposed to acidic or basic conditions. It is soluble in polar solvents like ethanol and acetone, but less soluble in non-polar solvents such as hexane.

How is 4-Dodecanolide (CAS: 2305-05-7) typically synthesized?

4-Dodecanolide (CAS: 2305-05-7) is usually synthesized through the esterification of dodecanol with a suitable acid, such as acetic acid, using a catalyst like sulfuric acid. The reaction is typically carried out under reflux conditions to drive the reaction to completion. The yield is generally around 90%, and the product can be purified by recrystallization from ethanol or acetone.

What industries use 4-Dodecanolide (CAS: 2305-05-7)?

4-Dodecanolide (CAS: 2305-05-7) is used in various industries. It is a key component in the production of fragrance and flavor compounds due to its pleasant floral and fruity aroma. It also finds applications in the pharmaceutical industry as a solubilizing agent and in the textile industry for improving the dyeability of fibers. Additionally, it is used in the formulation of certain cosmetic products and as a component in certain types of sensors.

What precautions should be taken when handling 4-Dodecanolide (CAS: 2305-05-7)?

When handling 4-Dodecanolide (CAS: 2305-05-7), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. It should be handled in a well-ventilated area or in a fume hood to avoid inhalation of the vapor. Spills should be cleaned up immediately using absorbent materials, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for emergency procedures and first aid instructions. Storage should be in a cool, dry place, away from sources of ignition and heat.