N~5~-(Diaminomethylene)-L-ornithyl-L-prolyl-N~5~-(diaminomethylene)-L-ornithyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine | CAS No. 229961-08-4

N~5~-(Diaminomethylene)-L-ornithyl-L-prolyl-N~5~-(diaminomethylene)-L-ornithyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine

Basic Information

CAS Number

229961-08-4

Molecular Formula

C64H103N21O14S

Molecular Weight

1422.73 g/mol

AD

Basic Physical Properties

CC(C)CC(C(=O)NC(CO)C(=O)NC(CC1=CN=CN1)C(=O)NC(CCCCN)C(=O)NCC(=O)N2CCCC2C(=O)NC(CCSC)C(=O)N3CCCC3C(=O)NC(CC4=CC=CC=C4)C(=O)O)NC(=O)C(CCCN=C(N)N)NC(=O)C5CCCN5C(=O)C(CCCN=C(N)N)N

InChI

InChI=1S/C64H103N21O14S/c1-37(2)30-44(79-53(89)42(18-10-25-73-64(69)70)77-58(94)49-20-12-27-84(49)60(96)40(66)16-9-24-72-63(67)68)54(90)82-47(35-86)56(92)80-45(32-39-33-71-36-75-39)55(91)76-41(17-7-8-23-65)52(88)74-34-51(87)83-26-11-19-48(83)57(93)78-43(22-29-100-3)61(97)85-28-13-21-50(85)59(95)81-46(62(98)99)31-38-14-5-4-6-15-38/h4-6,14-15,33,36-37,40-50,86H,7-13,16-32,34-35,65-66H2,1-3H3,(H,71,75)(H,74,88)(H,76,91)(H,77,94)(H,78,93)(H,79,89)(H,80,92)(H,81,95)(H,82,90)(H,98,99)(H4,67,68,72)(H4,69,70,73)/t40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-/m0/s1

InChIKey

KIODTAJAFBDDGP-TZIGXLGFSA-N

LogP

-4.882699999999993

Topological Polar Surface Area

560.7799999999999 Ų

Hydrogen Bond Donor/Acceptor

23 / 35

Complexity

2810

Synonyms & References

English

  • Apelin-12 (human, bovine, mouse, rat)
  • 229961-08-4
  • AKOS040757530
  • Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe
  • KIODTAJAFBDDGP-TZIGXLGFSA-N
  • APELIN-12
  • Apelin-12(human,bovine,mouse,rat)
  • PD166116
  • L-Phenylalanine,L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-
  • APELIN PRECURSOR (66-77) (HUMAN, BOVINE, MOUSE, RAT)
  • Apelin-12
  • Apelin-12,(Des-Gln1)-Apelin-13
  • H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
  • L-Phenylalanine,L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-proly...
  • (DES-GLN1)-APELIN-13 (HUMAN,BOVINE,MOUSE,RAT)
  • (Des-Gln1)-Apelin-13 (huMan,bovine,Mouse,rat),Apelin Precursor (66-77) (huMan,bovine,Mouse,rat),Preproapelin
  • APELIN 12
  • Apelin-12 (huMan,bovine,Mouse,rat) (Des-Gln1)-Apelin-13 (huMan,bovine,Mouse,rat),Apelin Precursor (66-77) (huMan,bovine,Mouse,rat),Preproapelin (66-77) (huMan,bovine,Mouse,rat)
  • ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE
  • RPRLSHKGPMPF-OH
  • (2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydro

MDL Number

MFCD05664679

FAQ

What regulatory guidelines apply to N~5~-(Diaminomethylene)-L-ornithyl-L-prolyl-N~5~-(diaminomethylene)-L-ornithyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine (CAS: 229961-08-4)?

N~5~-(Diaminomethylene)-L-ornithyl-L-prolyl-N~5~-(diaminomethylene)-L-ornithyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine (CAS: 229961-08-4) is subject to regulatory guidelines such as REACH for European manufacturers and importers, FDA for pharmaceutical applications, and EPA for environmental safety. It is important to comply with GHS classification for substance safety data sheets and ensure proper handling and storage to prevent hazards associated with this compound.

Are there alternatives to N~5~-(Diaminomethylene)-L-ornithyl-L-prolyl-N~5~-(diaminomethylene)-L-ornithyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine (CAS: 229961-08-4) in synthesis?

While N~5~-(Diaminomethylene)-L-ornithyl-L-prolyl-N~5~-(diaminomethylene)-L-ornithyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine (CAS: 229961-08-4) is a specific compound, alternatives can include similar peptides or amino acid sequences. Common alternative reagents include other peptides or amino acids, which can be used to modify or synthesize similar compounds for research or pharmaceutical applications.

What is the market or research trend for N~5~-(Diaminomethylene)-L-ornithyl-L-prolyl-N~5~-(diaminomethylene)-L-ornithyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine (CAS: 229961-08-4)?

The market for N~5~-(Diaminomethylene)-L-ornithyl-L-prolyl-N~5~-(diaminomethylene)-L-ornithyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine (CAS: 229961-08-4) is driven by its use in advanced pharmaceuticals and research. Recent trends indicate increasing interest in drug development and therapeutic applications. Research is focusing on the potential of this compound in treating various diseases, particularly those requiring targeted drug delivery systems.

How should waste containing N~5~-(Diaminomethylene)-L-ornithyl-L-prolyl-N~5~-(diaminomethylene)-L-ornithyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine (CAS: 229961-08-4) be handled?

Waste containing N~5~-(Diaminomethylene)-L-ornithyl-L-prolyl-N~5~-(diaminomethylene)-L-ornithyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine (CAS: 229961-08-4) should be collected and disposed of in accordance with local and national regulations. This may involve incineration, professional waste disposal services, or other environmentally friendly methods. It is crucial to ensure proper handling to prevent environmental contamination and comply with safety standards.

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