1-Phenyl-1,2,3,4-tetrahydroisoquinoline

Basic Information

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CAS Number

22990-19-8

Molecular Formula

C15H15N

Molecular Weight

209.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

98.0 to 102.0 deg-C

Boiling Point

338.4°C at 760 mmHg

Density

1.065

Flash Point

166.9 °C

Refractive Index

1.589

SMILES

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C1CNC(C2=CC=CC=C21)C3=CC=CC=C3

InChI

InChI=1S/C15H15N/c1-2-7-13(8-3-1)15-14-9-5-4-6-12(14)10-11-16-15/h1-9,15-16H,10-11H2

InChIKey

PRTRSEDVLBBFJZ-UHFFFAOYSA-N

LogP

2.9217000000000013

Topological Polar Surface Area

12.03 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

220

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

racemic 1-phenyl-1,2,3,4-tetrahydro-isoquinoline
NSC-338399
AKOS016040456
A4871
1-phenyl-1,2,3,4-tetrahydroisoquinoline;1-Phenyl-1,2,3,4-tetrahydro-isoquinoline
FT-0638277
BCP12873
EN300-72483
AC-685
NCGC00245237-01
SY030993
SCHEMBL12046710
BAS 01118689
Phenyl-TIQ
PD119414
SB34419
(S)-1,2,3,4-TETRAHYDRO-1-PHENYLISOQUINOLINE
NSC 338399
FT-0603857
BDBM50017035
rac 1-Phenyl-1,2,3,4-tetrahydroisoquinoline
CHEMBL21465
Q-101004
1-phenyl-1,2,3,4-tetrahydro-isoquinoline, AldrichCPR
CS-B0307
Z1741966190
MFCD02179241
BCP14564
P2056
1,2,3,4-Tetrahydro-1-phenylisoquinoline
A18116

MDL Number

MFCD02179241

Customs Code

2933499090

FAQ

What regulatory guidelines apply to 1-Phenyl-1,2,3,4-tetrahydroisoquinoline (CAS: 22990-19-8)?

1-Phenyl-1,2,3,4-tetrahydroisoquinoline (CAS: 22990-19-8) falls under the classification of Schedule II controlled substance in the United States. It is regulated under the Chemicals Regulation Directive (CRD) in the European Union and must comply with REACH regulations. Additionally, it is subject to the U.S. Food and Drug Administration (FDA) and Environmental Protection Agency (EPA) guidelines. Users must adhere to safety data sheet (SDS) requirements and follow local, state, and federal regulations.

Are there alternatives to 1-Phenyl-1,2,3,4-tetrahydroisoquinoline (CAS: 22990-19-8) in synthesis?

There are several alternatives to 1-Phenyl-1,2,3,4-tetrahydroisoquinoline (CAS: 22990-19-8) for synthesis, including 1-Phenylisoquinoline and 1-Phenyl-2,3-dihydroisoquinoline. These compounds can be used as substitutes depending on the specific reaction conditions and desired product. Common alternative reagents include phenylboronic acid and other aromatic amines. It is important to evaluate the chemical properties and reactivity of these alternatives to ensure they meet the requirements of the synthesis.

What is the market or research trend for 1-Phenyl-1,2,3,4-tetrahydroisoquinoline (CAS: 22990-19-8)?

Research on 1-Phenyl-1,2,3,4-tetrahydroisoquinoline (CAS: 22990-19-8) is focused on its potential as a lead compound for drug development, particularly in the treatment of neurological disorders and pain management. Market trends indicate increasing interest in natural products with therapeutic potential. The compound is also being explored for its anti-inflammatory and anti-cancer properties. Additionally, there is ongoing research into its synthesis and purification methods to improve its accessibility for further studies.

How should waste containing 1-Phenyl-1,2,3,4-tetrahydroisoquinoline (CAS: 22990-19-8) be handled?

Waste containing 1-Phenyl-1,2,3,4-tetrahydroisoquinoline (CAS: 22990-19-8) should be managed according to hazardous waste regulations. Waste liquids should be collected in suitable containers and stored in a secure, well-ventilated area. Incineration is a common method for disposal, but professional waste disposal services may be necessary for larger quantities. Environmental protection measures include minimizing the release of volatile organic compounds (VOCs) and ensuring proper containment to prevent soil and water contamination. It is crucial to follow local, state, and federal guidelines for waste disposal and ensure compliance with safety regulations.