Aspartame | CAS No. 22839-47-0

Aspartame

Basic Information

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CAS Number

22839-47-0

Molecular Formula

C14H18N2O5

Molecular Weight

294.31 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Powder

Melting Point

248-250 ºC

Boiling Point

535.8°C at 760 mmHg

Water Solubility

Soluble in formic acid, dimethyl sulfoxide. Sparingly soluble in water and ethanol.

Refractive Index

14.5 ° (C=4, 15mol/L Formic Acid)

Specific Rotation

15.5 º (c=4, 15N formic acid)

SMILES

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COC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)N)Cc1ccccc1

InChI

InChI=1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1

InChIKey

IAOZJIPTCAWIRG-QWRGUYRKSA-N

LogP

-0.31109999999999793

Topological Polar Surface Area

118.72 Å²

Hydrogen Bond Donor/Acceptor

4 / 7

Complexity

380

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Stability

Stable. Incompatible with strong oxidizing agents.

Synonyms & References

English

Aspartame
Equal
L-alpha-aspartyl-L-phenylalanine-methylester
L-Aspartyl-L-phenylalanine methyl ester
L-Phenylalanine, N-L-alpha-aspartyl-, 1-methyl ester
Nutrasweet
(S)-3-Amino-4-(((S)-1-methoxy-1-oxo-3-phenylpropan-2-yl)amino)-4-oxobutanoic acid
(S)-3-Amino-4-((S)-1-methoxy-1-oxo-3-phenylpropan-2-ylamino)-4-oxobutanoic acid
ASPARTAME(P)
OTAVA-BB 4435021
APM
ASPARTAM
Asp-Phe methyl ester
Asp-Phe-Ome
canderel
E 951
H-Asp-Phe-OMe
mer
N-(L-α-Aspartyl)-L-phenylalanine methyl ester
N-L-α-Aspartyl-L-phenylalanine 1-Methyl Ester
tri-sweet
Zero-Cal
Lepcu DDH-20
WAKO017-22611
湖北阿斯巴甜生产厂家
Aspartamum
Aspartamo
Aspartylphenylalanine methyl ester
Dipeptide sweetener
Methyl aspartylphenylalanate
Sweet dipeptide

MDL Number

MFCD00002724

Customs Code

2924299090

FAQ

What is Aspartame (CAS: 22839-47-0)?

Aspartame is an artificial sweetener with the chemical formula C14H18N2O5. It is a dipeptide composed of aspartic acid and phenylalanine, with a methyl ester group. Known for its intense sweetness and low caloric content, aspartame is widely used in food and beverages. It is stable under normal conditions but can degrade when exposed to heat or moisture. Aspartame is also used in pharmaceuticals as a flavoring agent.

What are the main uses of Aspartame (CAS: 22839-47-0)?

Aspartame is primarily used as a low-calorie sweetener in food, beverages, and pharmaceutical products. It is commonly found in diet sodas, chewing gum, and tabletop sweeteners. In the pharmaceutical industry, it is used to improve the taste of medications. Additionally, it serves as a research compound for studying sweet taste mechanisms and metabolic effects. Its high sweetness intensity and stability make it a popular alternative to sugar.

Is Aspartame (CAS: 22839-47-0) safe?

Aspartame is considered safe for consumption by regulatory agencies like the FDA and EFSA, with approved daily intake levels. However, individuals with phenylketonuria (PKU) should avoid it due to its phenylalanine content. Proper handling is necessary to prevent exposure to moisture or heat, which can affect its stability. Safety guidelines emphasize following recommended usage and storage practices to ensure optimal performance and safety.

How should Aspartame (CAS: 22839-47-0) be stored?

Aspartame should be stored in a cool, dry, and dark place to maintain its stability and prevent degradation. It is best kept in a sealed container at temperatures below 25°C and humidity levels below 60%. Avoid exposure to light, heat, or moisture to preserve its potency. Storage conditions significantly impact its shelf life and effectiveness as a sweetener.