Methyl 5-formyl-1,2-oxazole-3-carboxylate | CAS No. 22667-21-6

Methyl 5-formyl-1,2-oxazole-3-carboxylate

Basic Information

CAS Number

22667-21-6

Molecular Formula

C6H5NO4

Molecular Weight

155.11 g/mol

AD

Basic Physical Properties

Melting Point

72-73 ºC

Boiling Point

306 ºC

Flash Point

139 ºC

COC(=O)C1=NOC(=C1)C=O

InChI

InChI=1S/C6H5NO4/c1-10-6(9)5-2-4(3-8)11-7-5/h2-3H,1H3

InChIKey

RSOKVJLXFFQLLB-UHFFFAOYSA-N

LogP

0.2737

Topological Polar Surface Area

69.4 Ų

Hydrogen Bond Donor/Acceptor

0 / 5

Complexity

170

Synonyms & References

English

  • 22667-21-6
  • Methyl5-formylisoxazole-3-carboxylate
  • MFCD11656600
  • AKOS015951428
  • methyl 5-formyl-1,2-oxazole-3-carboxylate
  • EN300-222331
  • methyl 5-formyl-3-isoxazolecarboxylate
  • CS-0215104
  • methyl 5-formylisoxazole-3-carboxylate
  • SCHEMBL15784497
  • Z1255416539
  • methyl 5-formyl-1, 2-oxazole-3-carboxylate
  • DTXSID70648291
  • SY198220
  • 3-isoxazolecarboxylic acid,5-formyl-,methyl ester
  • Methyl 5-formyl-1,2-oxazole-3-carboxylate
  • 3-Carbomethoxy-5-Formylisoxazol
  • 5-formyl-isoxazole-3-carboxylic acid methyl ester

MDL Number

MFCD11656600

Customs Code

2934999090

FAQ

What are the physical and chemical properties of Methyl 5-formyl-1,2-oxazole-3-carboxylate (CAS: 22667-21-6)?

Methyl 5-formyl-1,2-oxazole-3-carboxylate (CAS: 22667-21-6) is a solid with a crystalline form. It has a molecular weight of approximately 163.18 g/mol and is slightly soluble in water. This compound is known for its reactivity, particularly in nucleophilic substitution reactions. It is commonly used in organic synthesis due to its functional groups.

How is Methyl 5-formyl-1,2-oxazole-3-carboxylate (CAS: 22667-21-6) typically synthesized?

Methyl 5-formyl-1,2-oxazole-3-carboxylate (CAS: 22667-21-6) can be synthesized via the condensation of acetic anhydride and oxazole-3-carboxylic acid in the presence of a suitable catalyst. This process typically yields high selectivity and good to excellent yields, making it a reliable method for large-scale production.

What industries use Methyl 5-formyl-1,2-oxazole-3-carboxylate (CAS: 22667-21-6)?

Methyl 5-formyl-1,2-oxazole-3-carboxylate (CAS: 22667-21-6) is primarily used in the pharmaceutical and chemical industries. It serves as a valuable intermediate in the synthesis of various drugs and organic compounds. Its unique functional groups also make it applicable in polymer and sensor manufacturing processes.

What precautions should be taken when handling Methyl 5-formyl-1,2-oxazole-3-carboxylate (CAS: 22667-21-6)?

When handling Methyl 5-formyl-1,2-oxazole-3-carboxylate (CAS: 22667-21-6), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. It should be stored in a cool, dry place away from direct sunlight. In case of spills, neutralize with water and dispose of in accordance with local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.

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