![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
Sitagliptin impurity 83 | CAS No. 2248445-00-1
Sitagliptin impurity 83
Basic Information
CAS Number
2248445-00-1
Molecular Formula
C14H14F3NO3
Molecular Weight
301.26 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
MDL Number
MFCD33401696
FAQ
What regulatory guidelines apply to Sitagliptin impurity 83 (CAS: 2248445-00-1)?
Sitagliptin impurity 83 (CAS: 2248445-00-1) is subject to various regulatory guidelines. In the European Union, it must comply with REACH regulations for registration, evaluation, authorization, and restriction of chemicals. In the U.S., the FDA and EPA have specific guidelines for the testing and handling of impurities in pharmaceuticals. GHS classification also applies, categorizing the compound based on its hazards. Proper documentation and adherence to these guidelines are essential for safe and legal use.
Are there alternatives to Sitagliptin impurity 83 (CAS: 2248445-00-1) in synthesis?
In the synthesis of sitagliptin, there are alternative reagents and methods that can be used to minimize the formation of impurities like Sitagliptin impurity 83 (CAS: 2248445-00-1). Common alternatives include using purer starting materials, optimizing reaction conditions, and employing chiral catalysts. These strategies can significantly reduce the presence of impurities and improve the overall yield and purity of the final product.
What is the market or research trend for Sitagliptin impurity 83 (CAS: 2248445-00-1)?
The market for Sitagliptin impurity 83 (CAS: 2248445-00-1) is closely tied to the development and production of sitagliptin-based medications. As research continues to explore sitagliptin's efficacy and potential for new applications, the need for high-quality impurity analysis and control will increase. Additionally, there is a growing focus on green chemistry and sustainable manufacturing processes, which may lead to new techniques for reducing impurities like Sitagliptin impurity 83 in the production of sitagliptin derivatives.
How should waste containing Sitagliptin impurity 83 (CAS: 2248445-00-1) be handled?
Handling waste containing Sitagliptin impurity 83 (CAS: 2248445-00-1) requires careful consideration of safety and environmental protection. Waste liquid should be collected in appropriate containers and stored in a secure, labeled area. For disposal, incineration is a common method, but professional waste disposal services should be used to ensure compliance with local regulations. Additionally, environmental precautions such as preventing leakage and ensuring proper ventilation should be maintained throughout the handling and disposal process to protect both human health and the environment.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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