Compound Q&A
Are there alternatives to Sitagliptin impurity 83 (CAS: 2248445-00-1) in synthesis?
Answer
In the synthesis of sitagliptin, there are alternative reagents and methods that can be used to minimize the formation of impurities like Sitagliptin impurity 83 (CAS: 2248445-00-1). Common alternatives include using purer starting materials, optimizing reaction conditions, and employing chiral catalysts. These strategies can significantly reduce the presence of impurities and improve the overall yield and purity of the final product.
About
CAS No
2248445-00-1
English Name
Sitagliptin impurity 83
Molecular Formula
C14H14F3NO3
Molecular Weight
301.26 g/mol
SMILES
C1COCCN1C(CC(=O)CC1C=C(F)C(=CC=1F)F)=O
InChIKey
CWJFNGNEUPHUID-UHFFFAOYSA-N
Last Updated: 2026-03-30 12:13
