2-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride (1:1) | CAS No. 224785-91-5

2-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride (1:1)

Basic Information

CAS Number

224785-91-5

Molecular Formula

C23H33ClN6O4S

Molecular Weight

525.08 g/mol

AD

Basic Physical Properties

Melting Point

227-230°C

CCCC1=NC(=C2N1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)CC)OCC)C.Cl

InChI

InChI=1S/C23H32N6O4S.ClH/c1-5-8-20-24-16(4)21-23(30)25-22(26-29(20)21)18-15-17(9-10-19(18)33-7-3)34(31,32)28-13-11-27(6-2)12-14-28;/h9-10,15H,5-8,11-14H2,1-4H3,(H,25,26,30);1H

InChIKey

XCMULUAPJXCOHI-UHFFFAOYSA-N

LogP

2.492220000000001

Topological Polar Surface Area

112.89999999999998 Ų

Hydrogen Bond Donor/Acceptor

1 / 10

Complexity

854

Safety Information

View Safety Information

GHS Hazard Pictograms

H301H301

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

  • s5957
  • 224785-90-4 (base)
  • Vardenafil, Hydrochloride Salt
  • 2-[2-ethoxy-5-(4-ethylpiperazin-1-yl)sulfonyl-phenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4-one trihydrate hydrochloride;Vardenafil
  • 224789-15-5
  • BAY 38-9456
  • AKOS032400217
  • Vardenafil hydrochloride
  • D09989
  • AC-30725
  • HY-B0442A
  • Vardenafil hydrochloride, United States Pharmacopeia (USP) Reference Standard
  • NSC759103
  • Vardenafil Hydrochloride Salt
  • Vardenafil hydrochloride trihydrate, >=98% (HPLC)
  • Nuviva
  • CHEMBL1339
  • Vardenafil hydrochloride trihydrate, European Pharmacopoeia (EP) Reference Standard
  • 224789-15-5 (di-hcl)
  • Vardenafil (hydrochloride)
  • Vardenafil hydrochloride [USAN]
  • SCHEMBL973820
  • 2-[2-ethoxy-5-(4-ethyl-piperazine-1-sulphonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one hydrochloride
  • IF61NL91H3
  • Piperazine, 1-((3-(1,4-dihydro-5-methyl-4-oxo-7-propylimidazo(5,1-f)(1,2,4)triazin-2-yl)-4-ethoxyphenyl)sulfonyl)-4-ethyl-, monohydrochloride
  • 224785-91-5
  • 2-(2-ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-onehydrochloride
  • 2-[2-ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylphenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4-one;hydrochloride
  • J-014731
  • UNII-IF61NL91H3
  • 2-(2-ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride

MDL Number

MFCD07369690

FAQ

What is 2-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride (1:1) (CAS: 224785-91-5)?

2-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride (1:1), with CAS number 224785-91-5, is a complex organic compound containing an imidazo[5,1-f][1,2,4]triazine ring system. It is a white to off-white solid and is commonly used in pharmaceutical research due to its structural versatility and potential biological activity. The compound is known for its solubility in polar solvents and stability under normal conditions.

What are the main uses of 2-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride (1:1) (CAS: 224785-91-5)?

This compound is primarily used in pharmaceutical research for developing drugs targeting neurological and cardiovascular conditions. Its structure allows for interactions with various biological targets, making it a valuable intermediate in the synthesis of bioactive molecules. It is also used in chemical synthesis and as a research reagent in laboratories studying drug mechanisms and molecular behavior.

Is 2-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride (1:1) (CAS: 224785-91-5) safe?

The safety of 2-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride (1:1) depends on its application. It is generally considered safe when handled properly in controlled laboratory environments. However, standard safety precautions such as wearing gloves, goggles, and a lab coat are recommended. It is important to follow OSHA and REACH guidelines for safe use and disposal.

How should 2-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride (1:1) (CAS: 224785-91-5) be stored?

This compound should be stored in a cool, dry, and light-protected environment, ideally at 2-8°C. It is recommended to keep it in a sealed container to prevent moisture absorption. Avoid exposure to air and direct sunlight to maintain its stability and efficacy. Proper storage conditions are essential to ensure the compound remains chemically intact and safe for use.

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