2-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one | CAS No. 224785-90-4

2-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one

Basic Information

CAS Number

224785-90-4

Molecular Formula

C23H32N6O4S

Molecular Weight

525.08 g/mol

AD

Basic Physical Properties

Melting Point

230-235ºC

Boiling Point

692.2°C at 760 mmHg

CCCC1=NC(=C2N1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)CC)OCC)C

InChI

InChI=1S/C23H32N6O4S/c1-5-8-20-24-16(4)21-23(30)25-22(26-29(20)21)18-15-17(9-10-19(18)33-7-3)34(31,32)28-13-11-27(6-2)12-14-28/h9-10,15H,5-8,11-14H2,1-4H3,(H,25,26,30)

InChIKey

SECKRCOLJRRGGV-UHFFFAOYSA-N

LogP

2.492220000000001

Topological Polar Surface Area

112.89999999999998 Ų

Hydrogen Bond Donor/Acceptor

1 / 10

Complexity

854

Safety Information

View Safety Information

Hazard Statement

H225 Highly Flammable liquid and vapor
Flammable liquids
H370 Causes damage to organs
Specific target organ toxicity, single exposure

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

  • AB01274740_03
  • BCP0726000254
  • BAY 38-9456
  • VARDENAFIL [WHO-DD]
  • BRD-K13926615-003-01-7
  • Vardenafil
  • VARDENAFIL [USAN]
  • 2-(2-Ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one
  • AB01275440-01
  • KS-5073
  • VARDENAFIL [INN]
  • VARDENAFIL [VANDF]
  • VARDENAFIL [EMA EPAR]
  • AB00698215-08
  • 2-(2-ethoxy-5-(4-ethylpiperazin-1-ylsulfonyl)phenyl)-5-methyl-7-propylimidazo[1,5-f][1,2,4]triazin-4(1H)-one
  • GTPL7320
  • DTXSID3048318
  • HSDB 7304
  • HMS3715F19
  • GS-6519
  • 224789-15-5
  • D08668
  • Vivanza
  • HMS2089K04
  • CCG-221149
  • Vardenafil (Vivanza)
  • G04BE09
  • 2-(2-ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one
  • BRD-K13926615-003-02-5
  • 1189685-70-8
  • VARDENAFIL [MI]

MDL Number

MFCD07773094

FAQ

What is 2-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one (CAS: 224785-90-4)?

2-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one (CAS: 224785-90-4) is a complex heterocyclic compound containing imidazo[5,1-f][1,2,4]triazine and piperazine rings. It exhibits solubility in organic solvents and is typically synthesized for specialized applications. Its molecular structure includes functional groups like sulfonyl, ethoxy, and propyl, contributing to its chemical reactivity and potential utility in advanced chemical processes.

What are the main uses of 2-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one (CAS: 224785-90-4)?

This compound is primarily used in pharmaceutical research as an intermediate for drug development, particularly in compounds targeting neurological or metabolic disorders. It also serves industrial applications in chemical synthesis and material science. Due to its structural complexity, it is utilized in laboratory settings for creating derivatives with tailored biological activities. Its specific uses depend on further functionalization and application context.

Is 2-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one (CAS: 224785-90-4) safe?

Safety data for this compound is limited, but standard precautions should be taken during handling. It may require protective measures such as gloves, goggles, and a fume hood to minimize exposure. While no specific toxicity information is available, adherence to general chemical safety guidelines and proper use of personal protective equipment (PPE) is recommended. Always consult the safety data sheet (SDS) for detailed handling instructions.

How should 2-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one (CAS: 224785-90-4) be stored?

This compound should be stored in a cool, dry place (ideally 2-8°C), away from light and moisture. It is best kept in a sealed, airtight container to maintain stability. Avoid exposure to heat and incompatible substances. Storage conditions may vary based on specific formulation, so following manufacturer guidelines is crucial for chemical stability and safety.

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