(2R,3R,3aS,9aR)-3-Hydroxy-2-(hydroxymethyl)-7-methyl-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one

Basic Information

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CAS Number

22423-26-3

Molecular Formula

C10H12N2O5

Molecular Weight

240.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Powder

Melting Point

217.0 to 221.0 deg-C

Boiling Point

452°C at 760 mmHg

Density

1.88

Flash Point

227.2 °C

Refractive Index

1.772

Specific Rotation

-43.0 to -46.0° (c=4 in H2O)

SMILES

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CC1=CN2C3C(C(C(O3)CO)O)OC2=NC1=O

InChI

InChI=1S/C10H12N2O5/c1-4-2-12-9-7(6(14)5(3-13)16-9)17-10(12)11-8(4)15/h2,5-7,9,13-14H,3H2,1H3/t5-,6-,7+,9-/m1/s1

InChIKey

WLLOAUCNUMYOQI-JAGXHNFQSA-N

LogP

-1.4366800000000002

Topological Polar Surface Area

93.81 Å²

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

432

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

TK-112690
2,2'-Anhydro-1-beta-arabinofuranosylthymine
2,2'-Anhydrothymidine
CHEMBL3251296
WLLOAUCNUMYOQI-JAGXHNFQSA-
6H-Furo(2',3':4,5)oxazolo(3,2-a)pyrimidin-6-one, 2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-7-methyl-, (2R-(2alpha,3beta,3abeta,9abeta))-
InChI=1/C10H12N2O5/c1-4-2-12-9-7(6(14)5(3-13)16-9)17-10(12)11-8(4)15/h2,5-7,9,13-14H,3H2,1H3/t5-,6-,7+,9-/m1/s1
6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one, 2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-7-methyl-, (2R,3R,3aS,9aR)-
WLLOAUCNUMYOQI-JAGXHNFQSA-N
F12166
(2R,4R,5R,6S)-5-hydroxy-4-(hydroxymethyl)-11-methyl-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one
2,2'-Anhydro-5-methyluridine
W-201933
6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one,2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-7-methyl-,(2R,3R,3aS,9aR)-
SCHEMBL13497182
(2R,4R,5R,6S)-5-hydroxy-4-(hydroxymethyl)-11-methyl-3,7-dioxa-1,9-diazatricyclo[6.4.0.0,2,6]dodeca-8,11-dien-10-one
(2R,3R,3aS,9aR)-3-Hydroxy-2-(hydroxymethyl)-7-methyl-3,3a-dihydro-2H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6(9aH)-one
AKOS015918519
3-Hydroxy-2-(hydroxymethyl)-7-methyl-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one
2,2'-Anhydro-athy
2.2'-Anhydro-5-methyluridine
O2,2'-Anhydro-5-methyluridine
2,2'-O-Anhydro-5-methyluridine
GQZ99GWR3T
UNII-GQZ99GWR3T
EN300-6732134
(2R,3R,3aS,9aR)-3-hydroxy-2-(hydroxymethyl)-7-methyl-2,3,3a,9a-tetrahydrofuro[[?]:[?]]oxazolo[[?]]pyrimidin-6-one
(2R,4R,5R,6S)-5-hydroxy-4-(hydroxymethyl)-11-methyl-3,7-dioxa-1,9-diazatricyclo[6.4.0.0,dodeca-8,11-dien-10-one
2,2'-Cyclothymidine
22423-26-3
2,2'-Anhydro-11-beta-D-arabinofuranosylthymine

MDL Number

MFCD00233555

FAQ

What is (2R,3R,3aS,9aR)-3-Hydroxy-2-(hydroxymethyl)-7-methyl-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one (CAS: 22423-26-3)?

This compound is a complex organic molecule with a unique structure. It is known for its distinctive ring system and contains hydroxyl and methyl groups. This molecule is not commonly used in everyday applications but is of interest in pharmaceutical research due to its potential biological activities.

What are the main uses of (2R,3R,3aS,9aR)-3-Hydroxy-2-(hydroxymethyl)-7-methyl-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one (CAS: 22423-26-3)?

This compound is primarily used in research and development, particularly in the pharmaceutical industry. It may be used as a starting material or intermediate in the synthesis of other compounds with biological activity. Its specific applications are limited due to its complex structure and specialized uses.

Is (2R,3R,3aS,9aR)-3-Hydroxy-2-(hydroxymethyl)-7-methyl-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one (CAS: 22423-26-3) safe?

This compound is generally safe when handled with appropriate precautions. However, it should be used in a well-ventilated area to avoid inhalation and direct contact with skin or eyes. Protective equipment such as gloves, goggles, and a lab coat is recommended. Ensure that it is stored in a secure container to prevent accidental exposure.

How should (2R,3R,3aS,9aR)-3-Hydroxy-2-(hydroxymethyl)-7-methyl-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one (CAS: 22423-26-3) be stored?

This compound should be stored in a cool, dry place away from direct sunlight and moisture. It should be kept in a properly sealed container to prevent degradation. Optimal storage conditions include a temperature range of 15-25°C and a relative humidity below 60%. Stability studies should be conducted to ensure the compound retains its integrity during storage.