Mirabegron | CAS No. 223673-61-8

Mirabegron

Basic Information

View in Editor

CAS Number

223673-61-8

Molecular Formula

C21H24N4O2S

Molecular Weight

396.51 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

138-140°C

Boiling Point

690°C at 760 mmHg

SMILES

View in Editor

O=C(Cc1csc(n1)N)Nc1ccc(cc1)CCNC[C@@H](c1ccccc1)O

InChI

InChI=1S/C21H24N4O2S/c22-21-25-18(14-28-21)12-20(27)24-17-8-6-15(7-9-17)10-11-23-13-19(26)16-4-2-1-3-5-16/h1-9,14,19,23,26H,10-13H2,(H2,22,25)(H,24,27)/t19-/m0/s1

InChIKey

PBAPPPCECJKMCM-IBGZPJMESA-N

LogP

2.772200000000001

Topological Polar Surface Area

100.27000000000001 Å²

Hydrogen Bond Donor/Acceptor

5 / 6

Complexity

467

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Mirabegron
2-(2-amino-1,3-thiazol-4-yl)-N-(4-{2-[(2-hydroxy-2-phenylethyl)amino]ethyl}phenyl)acetamide
2-Amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide
[14C]-Mirabegron
N-(4-(2-(2-hydroxy-2-phenylethylamino)ethyl)phenyl)-2-(2-aminothiazol-4-yl)acetamide
2-Amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenyl-ethyl]amino]-ethyl]phenyl]-4-thiazoleacetamide
4-Thiazoleacetamide, 2-amino-N-(4-(2-(((2R)-2-hydroxy-2-phenylethyl)amino)ethyl)phenyl)-
MIRABEQRON
YM 178
YM-178
2-(2-Amino-1,3-thiazol-4-yl)-N-[4-[2-[((2R)-2-hydroxy-2-phenylethyl)amino]ethyl]phenyl]acetamide
YM178(R)-Mirabegron
Mirabelon
Myrbetriq
Betanis
Mirabegron (YM178)
YM178
MVR3JL3B2V
Betmiga
(R)-2-(2-aminothiazol-4-yl)-N-(4-(2-((2-hydroxy-2-phenylethyl)amino)ethyl)phenyl)acetamide
Myrbetriq (TN)
2-(2-amino-1,3-thiazol-4-yl)-N-[4-(2-{[(2R)-2-hydroxy-2-phenylethyl]amino}ethyl)phenyl]acetamide
Mirabegron [USAN:INN]
2-(2-amino-1,3-thiazol-4-yl)-N-[4-[2-[[(2R)-

MDL Number

MFCD11100356

FAQ

What is Mirabegron (CAS: 223673-61-8)?

Mirabegron is a synthetic compound with the CAS number 223673-61-8. It is primarily known as a selective beta-3 adrenergic receptor agonist, used in the treatment of overactive bladder. Its chemical formula is C15H19N3O2S, and it is a white to off-white powder with good solubility in certain solvents. Mirabegron works by relaxing the bladder muscle, thereby increasing bladder capacity and reducing urinary frequency.

What are the main uses of Mirabegron (CAS: 223673-61-8)?

Mirabegron (CAS: 223673-61-8) is mainly used in pharmaceuticals as a treatment for overactive bladder. It is also utilized in research for studying beta-3 adrenergic receptor activation and its physiological effects. Additionally, it has potential applications in the development of drugs targeting urinary disorders and other conditions related to smooth muscle relaxation.

Is Mirabegron (CAS: 223673-61-8) safe?

Mirabegron (CAS: 223673-61-8) is generally considered safe when used as prescribed. However, it should be handled with care, especially in industrial or research settings, to avoid inhalation or skin contact. Safety protocols include wearing appropriate personal protective equipment (PPE) and following guidelines for handling chemical substances. It is approved for medical use by regulatory bodies and meets safety standards for pharmaceutical compounds.

How should Mirabegron (CAS: 223673-61-8) be stored?

Mirabegron (CAS: 223673-61-8) should be stored in a cool, dry place away from direct light. It is typically kept in a sealed container to maintain stability and prevent moisture ingress. Proper storage ensures the compound remains effective and safe for use. Storage conditions should be controlled to avoid degradation, and it should be kept out of reach of children and not exposed to incompatible materials.