ARV-471 | CAS No. 2229711-68-4

ARV-471

Basic Information

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CAS Number

2229711-68-4

Molecular Formula

C45H49N5O4

Molecular Weight

723.92 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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OC1=CC2CC[C@@H]([C@@H](C=2C=C1)C1C=CC(=CC=1)N1CCC(CN2CCN(CC2)C2=CC3CN([C@H]4CCC(=O)NC4=O)C(=O)C=3C=C2)CC1)C1C=CC=CC=1

InChI

InChI=1S/C45H49N5O4/c51-37-12-15-39-33(27-37)8-13-38(31-4-2-1-3-5-31)43(39)32-6-9-35(10-7-32)48-20-18-30(19-21-48)28-47-22-24-49(25-23-47)36-11-14-40-34(26-36)29-50(45(40)54)41-16-17-42(52)46-44(41)53/h1-7,9-12,14-15,26-27,30,38,41,43,51H,8,13,16-25,28-29H2,(H,46,52,53)/t38-,41+,43+/m1/s1

InChIKey

TZZDVPMABRWKIZ-XMOGEVODSA-N

LogP

6.053700000000006

Topological Polar Surface Area

96.43 Å²

Hydrogen Bond Donor/Acceptor

2 / 9

Complexity

1310

Synonyms & References

English

ARV-471
WC1U3R1YMI
(S)-3-(5-(4-((1-(4-(rel-(1R,2S)-6-Hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenyl)piperidin-4-yl)methyl)piperazin-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
2,6-Piperidinedione, 3-(1,3-dihydro-1-oxo-5-(4-((1-(4-((1R,2S)-1,2,3,4-tetrahydro-6-hydroxy-2-phenyl-1-naphthalenyl)phenyl)-4-piperidinyl)methyl)-1-piperazinyl)-2H-isoindol-2-yl)-, (3S)-
Unii-WC1U3R1ymi
Estrogen Receptor (ER) PROTAC Degrader Arv471
Vepdegestrant

FAQ

What regulatory guidelines apply to ARV-471 (CAS: 2229711-68-4)?

ARV-471 (CAS: 2229711-68-4) falls under the scope of the REACH regulations in the EU, which require registration, evaluation, authorization, and restriction of chemicals. In the U.S., it is also covered by the EPA and FDA guidelines for chemical substances. Proper documentation and compliance with these regulations are necessary to ensure safe handling and use.

Are there alternatives to ARV-471 (CAS: 2229711-68-4) in synthesis?

ARV-471 (CAS: 2229711-68-4) can be synthesized using alternative reagents and methods that offer similar functional properties. Common alternatives include analogs such as ARV-472 and ARV-473, which may have different substituents or structural modifications. These alternatives can be explored based on the specific needs and requirements of the synthesis process.

What is the market or research trend for ARV-471 (CAS: 2229711-68-4)?

ARV-471 (CAS: 2229711-68-4) is currently under active research and development for its potential applications in the pharmaceutical industry. Market trends indicate growing interest in its use as a potential therapeutic agent for various diseases, particularly in oncology. Research is also focusing on optimizing its delivery systems and improving its bioavailability.

How should waste containing ARV-471 (CAS: 2229711-68-4) be handled?

Waste containing ARV-471 (CAS: 2229711-68-4) should be collected in appropriate containers and handled according to the waste management guidelines provided by local authorities. Incineration or professional waste disposal methods should be used to ensure safe and environmentally friendly disposal. Precautions should be taken to prevent the spread of the compound into the environment during handling and disposal.