(1R,2R)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride (1:1) | CAS No. 22204-88-2

(1R,2R)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride (1:1)

Basic Information

CAS Number

22204-88-2

Molecular Formula

C16H26ClNO2

Molecular Weight

299.84 g/mol

AD

Basic Physical Properties

Melting Point

171ºC

CN(C)CC1CCCCC1(C2=CC(=CC=C2)OC)O.Cl

InChI

InChI=1S/C16H25NO2.ClH/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3;/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3;1H/t14-,16+;/m1./s1

InChIKey

PPKXEPBICJTCRU-XMZRARIVSA-N

LogP

3.0564000000000027

Topological Polar Surface Area

32.7 Ų

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

282

Safety Information

View Safety Information

Hazard Statement

H225 Highly Flammable liquid and vapor
Flammable liquids
H370 Causes damage to organs
Specific target organ toxicity, single exposure

Toxicity

LD50 in mice, rats (mg/kg): 350, 228 orally; 200, 286 s.c. (Lagler)

Synonyms & References

English

  • 148229-78-1
  • Bellatram
  • TRAMADOL HYDROCHLORIDE CIV [USP-RS]
  • Tramadol ER
  • (+-)-tramadol hydrochloride
  • Tridol
  • Tradol-Puren
  • Tramadol Hydrochloride (1.0 mg/mL in Methanol)
  • PPKXEPBICJTCRU-XMZRARIVSA-N
  • TRAMADOL HYDROCHLORIDE [EP MONOGRAPH]
  • SMR000449308
  • (1R,2R)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol Hydrochloride
  • NS00134332
  • TRAMADOL HYDROCHLORIDE (EP MONOGRAPH)
  • NCGC00159343-02
  • CCG-101135
  • QDOLO
  • EINECS 252-950-2
  • TRAMADOL HYDROCHLORIDE [HSDB]
  • (+)-(1R,2R)-Tramadol hydrochloride
  • DTXSID7023691
  • MLS000758218
  • TRAMADOL HYDROCHLORIDE [JAN]
  • Tramal
  • Contramal
  • cis-Tramadol hydrochloride
  • Tramed
  • Rybix
  • NSC-759105
  • (R,R)-tramadol hydrochloride
  • Mabron

MDL Number

MFCD00798507

Customs Code

2922509090

FAQ

What is (1R,2R)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride (CAS: 22204-88-2)?

(1R,2R)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride is a chiral compound with a hydrochloride salt form. It has a molecular formula of C17H27NO2.HCl and a molecular weight of approximately 293.84 g/mol. It is a white or off-white powder with a slight odor and is soluble in water and organic solvents.

What are the main uses of (1R,2R)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride (CAS: 22204-88-2)?

(1R,2R)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride is primarily used as an intermediate in the synthesis of pharmaceuticals and other chemical compounds. It is also used in research and development for its unique chemical properties.

Is (1R,2R)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride (CAS: 22204-88-2) safe?

The safety of (1R,2R)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride depends on proper handling and storage. It is classified as a non-toxic compound, but it should be handled with care to avoid inhalation, skin contact, and eye exposure. Protective measures include the use of gloves, goggles, and appropriate laboratory attire.

How should (1R,2R)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride (CAS: 22204-88-2) be stored?

(1R,2R)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride should be stored in a cool, dry place, away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent moisture and contamination. The optimal temperature range for storage is 15-25°C (59-77°F), and relative humidity should be maintained below 60%.

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