2-[(2-Methoxyphenoxy)methyl]oxirane

Basic Information

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CAS Number

2210-74-4

Molecular Formula

C10H12O3

Molecular Weight

180.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Powder

Melting Point

37.0 to 41.0 deg-C

Boiling Point

265.3°C at 760 mmHg

Density

1.142

Flash Point

87.4 °C

Refractive Index

1.526

SMILES

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COC1=CC=CC=C1OCC2CO2

InChI

InChI=1S/C10H12O3/c1-11-9-4-2-3-5-10(9)13-7-8-6-12-8/h2-5,8H,6-7H2,1H3

InChIKey

RJNVSQLNEALZLC-UHFFFAOYSA-N

LogP

1.4728

Topological Polar Surface Area

30.990000000000002 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

160

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H341 Suspected of causing genetic defects
Germ cell mutagenicity

Synonyms & References

English

Guajacol-glycidaether
EC 218-644-8
AC-5902
1-(2-methoxyphenyloxy)-2,3-epoxypropane
MFCD00190158
WLN: T3OTJ B1OR BO1
1,2-Epoxy-3-(o-methoxyphenoxy)propane
DS-2271
NSC 133442
1-methoxy-2-(oxiranylmethoxy) benzene
AKOS016051052
CS-W017203
G0416
NSC112256
Oxirane,2-[(2-methoxyphenoxy)methyl]-
2-METHOXY-1-(OXIRANYLMETHOXY)BENZENE
2210-74-4
2-[(2-Methoxyphenoxy)methyl]oxirane; Ranolazine Related Compound A
DTXSID601292484
GLYCIDYL O-METHOXYPHENYL ETHER
1,2-Epoxy-3-(2-methoxyphenoxy)propane
[(2-methoxyphenoxy)methyl]oxirane;1,2-epoxy-3-(o-methoxyphenoxy)-propan;1,2-epoxy-3-(o-methoxyphenoxy)propane;3-(2-Methoxphenoxy)-1,2-epoxypropane;guajacol-glycidaether;2-[(2-Methoxyphenoxy)methyl]oxirane
AKOS000122885
UNII-Z96AT4ECV6
AMY8958
1-(o-methoxy-phenoxy)-2,3-epoxypropane
NSC-133442
NSC133442
( inverted exclamation markA)-2-[(2-Methoxyphenoxy)methyl]oxirane
BENZENE, 1-(2,3-EPOXYPROPOXY)-2-METHOXY-
EINECS 218-644-8

MDL Number

MFCD00190158

Customs Code

2910900090

FAQ

What are the physical and chemical properties of 2-[(2-Methoxyphenoxy)methyl]oxirane (CAS: 2210-74-4)?

2-[(2-Methoxyphenoxy)methyl]oxirane is a colorless, flammable liquid with a molecular weight of approximately 176.23 g/mol. It has a low solubility in water but is soluble in organic solvents. This compound is highly reactive and prone to ring-opening polymerization under basic conditions. For storage, maintain at room temperature and avoid prolonged exposure to light and heat.

How is 2-[(2-Methoxyphenoxy)methyl]oxirane (CAS: 2210-74-4) typically synthesized?

2-[(2-Methoxyphenoxy)methyl]oxirane is synthesized via a two-step reaction involving the coupling of a phenol derivative with oxirane followed by methylation. Common catalysts include palladium-based complexes, and the process typically yields a high purity product with good selectivity. Detailed synthetic procedures can be found in the literature and patents.

What industries use 2-[(2-Methoxyphenoxy)methyl]oxirane (CAS: 2210-74-4)?

2-[(2-Methoxyphenoxy)methyl]oxirane is primarily used in the pharmaceutical industry for the synthesis of intermediates and in the polymer industry as a monomer. It also finds applications in the development of sensors and semiconductors due to its unique chemical reactivity and structural properties.

What precautions should be taken when handling 2-[(2-Methoxyphenoxy)methyl]oxirane (CAS: 2210-74-4)?

When handling 2-[(2-Methoxyphenoxy)methyl]oxirane, use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work in a well-ventilated area or a fume hood. Ensure proper storage in a cool, dry place away from sources of heat and light. In case of spill, immediately clean up with an appropriate absorbent material and dispose of according to safety data sheet (SDS) guidelines.