N-Isopropylacrylamide

Basic Information

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CAS Number

2210-25-5

Molecular Formula

C6H11NO

Molecular Weight

113.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Physical Properties

Melting Point

60-63 °C <br />63-67 °C

Boiling Point

89-92 °C/2 mmHg

Water Solubility

Slightly soluble in water.

Flash Point

119.7℃

Refractive Index

1.4210 (estimate)

SMILES

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CC(C)NC(=O)C=C

InChI

InChI=1S/C6H11NO/c1-4-6(8)7-5(2)3/h4-5H,1H2,2-3H3,(H,7,8)

InChIKey

QNILTEGFHQSKFF-UHFFFAOYSA-N

LogP

0.6969999999999998

Topological Polar Surface Area

29.1 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

96.7

Safety Information

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GHS Hazard Pictograms

H302

H319

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Sensitiveness

热敏感

Synonyms & References

English

N-Isopropylacrylamide
AKOS 91289
Isopropyl acrylamide
ISOPROPYLACRYLAMIDE(N-)
2-Propenamide, N-(1-methylethyl)-
Isopropylamid kyseliny akrylove
n-(1-methylethyl)-2-propenamid
N-(1-methylethyl)-2-Propenamide
n-isopropyl-acrylamid
Acrylamide, N-isopropyl.
N-Isopropylacrylamide (stabilized with MEHQ)
N-propan-2-ylprop-2-enamide
2-Propenamide,N-(1-methylethyl)
Acrylamide,N-isopropyl
N-(isopropyl)acrylamide
Nipam
N-Isopropylacrylamide,stabilized
n-isopropyl-acrylamide
N-Iso-Propylacrylamide
Acrylamide, N-isopropyl-
N-Isopropyl acrylamide
B7GFF17L9U
QNILTEGFHQSKFF-UHFFFAOYSA-N
Isopropylamid kyseliny akrylove [Czech]
N-Isopropylacrylamide, stabilized with MEHQ
NIPAM
n-(1-methylethyl)-2-propenamide
isopropyl acrylamide

MDL Number

MFCD00041913

Customs Code

2924199090

FAQ

What is N-Isopropylacrylamide (CAS: 2210-25-5)?

N-Isopropylacrylamide (CAS: 2210-25-5) is a chemical compound with the formula C5H11NO2. It is a white, odorless solid that is soluble in water and various organic solvents. This compound is known for its temperature-responsive properties, making it useful in applications such as smart materials and drug delivery systems. Its hydrophilic nature and ability to form thermoresponsive polymers are key characteristics.

What are the main uses of N-Isopropylacrylamide (CAS: 2210-25-5)?

N-Isopropylacrylamide (CAS: 2210-25-5) is widely used in pharmaceuticals for developing temperature-sensitive drug delivery systems. It finds applications in industrial coatings, adhesives, and polymer synthesis. In food science, it is employed in controlled release systems for flavor and nutrient delivery. Additionally, it is utilized in research for creating stimuli-responsive materials and in biomedical engineering for smart hydrogels.

Is N-Isopropylacrylamide (CAS: 2210-25-5) safe?

N-Isopropylacrylamide (CAS: 2210-25-5) is considered toxic if inhaled or ingested and may cause skin and eye irritation. Safety measures include using personal protective equipment (PPE) like gloves and goggles, and working in well-ventilated areas. It should be handled according to OSHA and REACH guidelines to ensure compliance with safety standards and minimize health risks.

How should N-Isopropylacrylamide (CAS: 2210-25-5) be stored?

N-Isopropylacrylamide (CAS: 2210-25-5) should be stored in a cool, dry place at 20-25°C, away from direct light. It requires airtight containers made of glass or HDPE to prevent moisture absorption. Proper storage ensures stability and maintains its chemical integrity, avoiding exposure to heat or humidity to prevent degradation.