Apixaban Open Chain Acid Impurity | CAS No. 2206825-87-6

Apixaban Open Chain Acid Impurity

Basic Information

CAS Number

2206825-87-6

Molecular Formula

C25H27N5O5

Molecular Weight

477.52 g/mol

AD

Basic Physical Properties

Melting Point

NA

Boiling Point

NA

COc1ccc(cc1)n2nc(C(=O)N)c3CCN(C(=O)c32)c4ccc(NCCCCC(=O)O)cc4

InChI

InChI=1S/C25H27N5O5/c1-35-19-11-9-18(10-12-19)30-23-20(22(28-30)24(26)33)13-15-29(25(23)34)17-7-5-16(6-8-17)27-14-3-2-4-21(31)32/h5-12,27H,2-4,13-15H2,1H3,(H2,26,33)(H,31,32)

InChIKey

JYXZVSMVCZWUPI-UHFFFAOYSA-N

LogP

2.849500000000001

Topological Polar Surface Area

139.77999999999997 Ų

Hydrogen Bond Donor/Acceptor

4 / 10

Complexity

751

Safety Information

View Safety Information

Hazard Statement

Synonyms & References

English

  • 5-((4-(3-Carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)amino)pentanoic acid
  • 5-4-3-(Aminocarbonyl)-1,4,5,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6H-pyrazolo3,4-cpyridin-6-ylphenylaminopentanoic Acid
  • 5-((4-(3-Carbamoyl-1-(4-methoxyphenyl)-7-oxo-1,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridin-6-yl)phenyl)amino)pentanoic acid

MDL Number

MFCD31690935

FAQ

What regulatory guidelines apply to Apixaban Open Chain Acid Impurity (CAS: 2206825-87-6)?

Apixaban Open Chain Acid Impurity (CAS: 2206825-87-6) must comply with the EU REACH regulations, which require registration, evaluation, authorization, and restriction of chemicals. Additionally, it should adhere to the GHS classification and labeling standards for hazardous chemicals. For FDA/US EPA requirements, it is crucial to ensure that the compound meets the safety and environmental standards, especially in pharmaceutical and agricultural applications.

Are there alternatives to Apixaban Open Chain Acid Impurity (CAS: 2206825-87-6) in synthesis?

In synthesis, Apixaban Open Chain Acid Impurity (CAS: 2206825-87-6) can be replaced by other similar compounds like Apixaban itself or its structural analogs such as rivaroxaban. Common alternative reagents include dicarboxylic acids and their derivatives, which can serve as efficient substitutes in various chemical reactions.

What is the market or research trend for Apixaban Open Chain Acid Impurity (CAS: 2206825-87-6)?

The market for Apixaban Open Chain Acid Impurity (CAS: 2206825-87-6) is closely tied to the broader market for Apixaban, a direct oral anticoagulant. Research trends show a focus on optimizing synthesis methods to reduce impurities and improve drug stability. Additionally, there is increasing interest in developing more efficient and sustainable processes for its production, driven by environmental and regulatory pressures.

How should waste containing Apixaban Open Chain Acid Impurity (CAS: 2206825-87-6) be handled?

Waste containing Apixaban Open Chain Acid Impurity (CAS: 2206825-87-6) should be handled according to local and international hazardous waste regulations. Collect waste in appropriate containers, label them properly, and dispose of them through a licensed waste management company. For incineration, ensure that the process meets all safety and emission standards. Always follow environmental protection precautions to minimize the impact on the environment and public health.

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