(1R)-1-(4-methoxyphenyl)ethan-1-amine

Basic Information

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CAS Number

22038-86-4

Molecular Formula

C9H13NO

Molecular Weight

151.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Melting Point

<-20°C

Boiling Point

65°C 0,4mm

Water Solubility

Soluble in water (10g/L).

Flash Point

65°C/0.38mm

Refractive Index

1.533

Specific Rotation

32 º (neat)

SMILES

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CC(C1=CC=C(C=C1)OC)N

InChI

InChI=1S/C9H13NO/c1-7(10)8-3-5-9(11-2)6-4-8/h3-7H,10H2,1-2H3/t7-/m1/s1

InChIKey

JTDGKQNNPKXKII-SSDOTTSWSA-N

LogP

1.7148999999999999

Topological Polar Surface Area

35.25 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

108

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Air Sensitive

Synonyms & References

English

(r)-(+)-1-(4-methoxy-phenyl)-ethylamine
F11221
DTXSID90348903
((R)-alpha-Methyl-p-Methoxybenzyl)amine
Z1127664169
r-(+)-1-(4-methoxyphenyl)ethylamine
(1R)-1-[4-(methyloxy)phenyl]ethanamine
(R)-1-(4-methoxy-phenyl)-ethanamine
(R)-1-(4-Methoxy-phenyl)-ethylamine
(R)-(+)-4-Methoxy-A-methylbenzylamine
(R)-1-(4-methoxyphenyl)ethanamine
AS-13190
(R)-(+)-4-Methoxy- alpha -methylbenzylamine
(R)-p-Methoxy-alpha-methylbenzylamine
(1R)-1-(4-methoxyphenyl)ethan-1-amine
AM20030368
(1R)-1-(4-methoxyphenyl)ethylamine
1-(4-Methoxyphenyl)ethanamine, (1R)-
NS00077378
EN300-112623
J-502125
Benzenemethanamine, 4-methoxy-alpha-methyl-, (alphaR)-
(R)-(+)-4-Methoxy-alpha-methylbenzylamine, >=95.0% (GC)
(R)-(+)-1-(4-Methoxyphenyl)ethylamine
(R)-1-(4-Methoxyphenyl)ethylamine
SCHEMBL57137
CS-W019916
(R)-1-(4-methoxyphenyl)-ethylamine
EC 606-907-3
AKOS015851877
(1R)-1-(4-methoxyphenyl)ethanamine

MDL Number

MFCD00671659

Customs Code

29222990

FAQ

What are the physical and chemical properties of (1R)-1-(4-methoxyphenyl)ethan-1-amine (CAS: 22038-86-4)?

(1R)-1-(4-methoxyphenyl)ethan-1-amine is a colorless to white crystalline solid with a molecular weight of approximately 184.23 g/mol. It has a moderate solubility in common organic solvents but is poorly soluble in water. This compound exhibits amine reactivity and can undergo nucleophilic aromatic substitution reactions.

How is (1R)-1-(4-methoxyphenyl)ethan-1-amine (CAS: 22038-86-4) typically synthesized?

(1R)-1-(4-methoxyphenyl)ethan-1-amine can be synthesized through a multistep reaction involving the coupling of 4-methoxyphenyl isocyanate with ethanolamine. The synthesis typically involves the use of a base catalyst and requires careful control of reaction conditions to achieve high selectivity and yield.

What industries use (1R)-1-(4-methoxyphenyl)ethan-1-amine (CAS: 22038-86-4)?

(1R)-1-(4-methoxyphenyl)ethan-1-amine is used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also utilized in the polymer industry for the modification of polymers and in the semiconductor industry for use in chemical vapor deposition processes.

What precautions should be taken when handling (1R)-1-(4-methoxyphenyl)ethan-1-amine (CAS: 22038-86-4)?

When handling (1R)-1-(4-methoxyphenyl)ethan-1-amine, it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. It should be stored in a cool, well-ventilated area away from heat sources. In case of a spill, immediately clean up with appropriate PPE and consult the Safety Data Sheet (SDS) for specific instructions.