Hydrocortisone hemisuccinate

Basic Information

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CAS Number

2203-97-6

Molecular Formula

C25H34O8

Molecular Weight

462.53 g/mol

Basic Physical Properties

Melting Point

No data available

Boiling Point

685.5°Cat760mmHg

Density

1.33

Flash Point

231.1°C

Solubility

Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)

Refractive Index

1.586

SMILES

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OC(=O)CCC(=O)OCC(=O)[C@@]1(O)CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2CCC2=CC(=O)CC[C@]12C

InChI

InChI=1S/C25H34O8/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30/h11,16-18,22,27,32H,3-10,12-13H2,1-2H3,(H,29,30)/t16-,17-,18-,22+,23-,24-,25-/m0/s1

InChIKey

VWQWXZAWFPZJDA-CGVGKPPMSA-N

LogP

2.1972999999999985

Topological Polar Surface Area

138.2 Å²

Hydrogen Bond Donor/Acceptor

3 / 8

Complexity

908

Synonyms & References

English

hydrocortisone 21-hemisuccinate*free acid
hydrocortisone 21-(hydrogen succinate)
Hydrocortisone Hemisuccinate
11b,17a,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate
Hydrocortisone hydrogen succinate
Hydrocortisone 21-hemisuccinate
Hydrocortisone succinate
CORTISOL 21-HEMISUCCINATE
CORTISOL HEMISUCCINATE
cortisol,hydrogensuccinate
cortisolsuccinate
Hydrocortisone 21-he
hydrocortisone hemisuccinate ester
hydrocortisone-21-O-hemisuccinate
Hydrocortizone Succinate
saxizon
Hydrocortisone hemisuccinate
4-(2-((8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethoxy)-4-oxobutanoic acid

MDL Number

MFCD00046256

FAQ

What regulatory guidelines apply to Hydrocortisone hemisuccinate (CAS: 2203-97-6)?

Hydrocortisone hemisuccinate (CAS: 2203-97-6) is subject to various regulatory guidelines, including GHS classification, REACH regulations, and FDA/EPA requirements. It is classified as a steroid hormone and anti-inflammatory agent. Manufacturers must adhere to strict guidelines for handling, storage, and disposal to ensure safety and environmental compliance.

Are there alternatives to Hydrocortisone hemisuccinate (CAS: 2203-97-6) in synthesis?

Hydrocortisone hemisuccinate (CAS: 2203-97-6) is often synthesized using alternatives like hydrocortisone acetate or other hemisuccinate derivatives. These alternatives offer similar anti-inflammatory properties and can be used as substitutes depending on the specific application and availability. Researchers and manufacturers should consider the cost, efficacy, and regulatory status of these alternatives.

What is the market or research trend for Hydrocortisone hemisuccinate (CAS: 2203-97-6)?

The market for hydrocortisone hemisuccinate (CAS: 2203-97-6) is stable, with a focus on its use in dermatological and ophthalmological applications. Research trends include developing more targeted formulations and exploring its potential in other therapeutic areas. Market trends show increasing demand for formulations that combine hydrocortisone hemisuccinate with other active ingredients to enhance efficacy and reduce side effects.

How should waste containing Hydrocortisone hemisuccinate (CAS: 2203-97-6) be handled?

Waste containing hydrocortisone hemisuccinate (CAS: 2203-97-6) should be collected in sealed containers, labeled appropriately, and disposed of through professional waste disposal services. Environmental precautions include minimizing exposure to water sources and soil. Incineration is a common method of disposal, but ensure compliance with local regulations to avoid environmental contamination.