6-(Difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-2-{[1-(methylsulfonyl)-4-piperidinyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one | CAS No. 2185857-97-8

6-(Difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-2-{[1-(methylsulfonyl)-4-piperidinyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one

Basic Information

CAS Number

2185857-97-8

Molecular Formula

C20H27F2N5O4S

Molecular Weight

471.53 g/mol

AD

Basic Physical Properties

O=C1C(C(F)F)=CC2=CN=C(NC3CCN(S(=O)(C)=O)CC3)N=C2N1[C@H]4[C@](C)(O)CCC4

InChI

InChI=1S/C20H27F2N5O4S/c1-20(29)7-3-4-15(20)27-17-12(10-14(16(21)22)18(27)28)11-23-19(25-17)24-13-5-8-26(9-6-13)32(2,30)31/h10-11,13,15-16,29H,3-9H2,1-2H3,(H,23,24,25)/t15-,20-/m1/s1

InChIKey

QIEKHLDZKRQLLN-FOIQADDNSA-N

LogP

2.0409999999999995

Topological Polar Surface Area

117.42 Ų

Hydrogen Bond Donor/Acceptor

2 / 9

Complexity

859

Synonyms & References

English

  • 3B512HJD65
  • 6-(difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-2-{[1-(methylsulfonyl)piperidin-4-yl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one
  • Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-(difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-2-[[1-(methylsulfonyl)-4-piperidinyl]amino]-
  • Ebvaciclib
  • 6-(Difluoromethyl)-8-((1R,2R)-2-hydroxy-2-methylcyclopentyl)-2-((1-(methylsulfonyl)piperidin-4-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
  • 6-(difluoromethyl)-8-((
  • PF-06873600

MDL Number

MFCD31807623

FAQ

What regulatory guidelines apply to 6-(Difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-2-{[1-(methylsulfonyl)-4-piperidinyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one (CAS: 2185857-97-8)?

Regulatory guidelines for this compound include the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH regulations in the EU, and FDA/EPA related requirements for safety and environmental impact. Proper hazard communication and storage are essential for compliance.

Are there alternatives to 6-(Difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-2-{[1-(methylsulfonyl)-4-piperidinyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one (CAS: 2185857-97-8) in synthesis?

Alternative reagents and synthetic pathways can vary based on the desired properties. Common alternatives include isomers and analogs, such as 6-fluoropyrimidine derivatives, which may offer similar or enhanced functionalities in various applications.

What is the market or research trend for 6-(Difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-2-{[1-(methylsulfonyl)-4-piperidinyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one (CAS: 2185857-97-8)?

Research trends for this compound focus on its potential in pharmaceuticals and biotechnology. Market trends indicate increasing demand due to its unique chemical structure and therapeutic potential. Emerging research areas include its application in targeted drug delivery systems and as a lead compound for new drug development.

How should waste containing 6-(Difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-2-{[1-(methylsulfonyl)-4-piperidinyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one (CAS: 2185857-97-8) be handled?

Waste containing this compound should be collected and stored in chemically compatible containers. Proper incineration or professional waste disposal methods should be utilized to ensure environmental safety. Precautions include monitoring for hazardous emissions and adhering to local environmental protection regulations.

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