Bupivacaine | CAS No. 2180-92-9

Bupivacaine

Basic Information

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CAS Number

2180-92-9

Molecular Formula

C18H28N2O

Molecular Weight

288.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

107.5-108°

Boiling Point

430.65°C (rough estimate)

Flash Point

140.9°C

Refractive Index

1.5700 (estimate)

SMILES

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CCCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C

InChI

InChI=1S/C18H28N2O/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21)

InChIKey

LEBVLXFERQHONN-UHFFFAOYSA-N

LogP

log Kow = 3.41

pKa

8.09; also reported as 8.17(at 25℃)

Complexity

321

Synonyms & References

English

Spectrum4_001098
3-Ethyl-2-methylbenzoxazoliumiodide
1-butyl-N-(2,6-dimethylphenyl)-piperidine-2-carboxamide
Bupivacaina [INN-Spanish]
BS-5224
C07529
EN300-18292932
Posimir
AKOS001637202
18010-40-7 (HCl)
DTXSID2022703
Marcaine and Sensorcaine
(+/-)-Bupivacaine
Y8335394RO
BCP12242
Bucaine (TN)
BRD-A01636364-003-05-2
1-Butyl-N-(2 pound not6-dimethylphenyl)piperidine-2-carboxamide
Bucaine
Exparel (TN)
AB00053674_11
NCGC00178579-02
KBioGR_001516
Bloqueina
SPBio_002489
SKY 0402
N01BB01
(.+/-.)-1-Butyl-2',6'-pipecoloxylidide
BCP21825
2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-, (.+/-.)-
HSDB 7790

MDL Number

MFCD00243007

FAQ

What regulatory guidelines apply to Bupivacaine (CAS: 2180-92-9)?

Bupivacaine (CAS: 2180-92-9) is classified as a local anesthetic and is subject to various regulatory guidelines. It must comply with the GHS (Globally Harmonized System of Classification and Labeling of Chemicals) for safety labeling. In Europe, it falls under the REACH regulations, which require manufacturers to register chemicals. In the U.S., the FDA regulates its use as a pharmaceutical product, and the EPA oversees its environmental impacts.

Are there alternatives to Bupivacaine in synthesis?

Yes, there are alternatives to Bupivacaine in synthesis, including other local anesthetics like ropivacaine and levobupivacaine. These alternatives offer similar efficacy but with different pharmacokinetic profiles. Researchers often explore these alternatives to improve safety and duration of action in clinical applications.

What is the market or research trend for Bupivacaine (CAS: 2180-92-9)?

Bupivacaine (CAS: 2180-92-9) remains a significant player in the local anesthetic market due to its broad clinical use. Research trends focus on optimizing its use in regional and epidural anesthesia. Emerging studies aim to reduce potential side effects and improve the drug's efficiency. Market trends show a steady demand, with a focus on reducing healthcare costs and enhancing patient outcomes.

How should waste containing Bupivacaine (CAS: 2180-92-9) be handled?

Waste containing Bupivacaine (CAS: 2180-92-9) should be collected and disposed of in accordance with local regulations. It is recommended to use professional waste disposal services due to its hazardous nature. Proper incineration or chemical treatment is necessary to ensure complete degradation and prevent environmental contamination. Always follow safety guidelines and ensure proper personal protective equipment is used during handling.