Apelin-17(human, bovine)

Basic Information

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CAS Number

217082-57-0

Molecular Formula

C96H156N34O20S

Molecular Weight

2138.55 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Density

1.49±0.1 g/cm3(Predicted)

Water Solubility

Soluble to 1.20 mg/ml in water

SMILES

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S(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(C(N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1C([H])=C([H])C([H])=C([H])C=1[H])=O)=O)N([H])C([C@]1([H])C([H])([H])C([H])([H])C([H])([H])N1C(C([H])([H])N([H])C([C@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])N([H])C([C@]([H])(C([H])([H])C1=C([H])N([H])C([H])=N1)N([H])C([C@]([H])(C([H])([H])O[H])N([H])C([C@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])N([H])C([C@]([H])(C([H])([H])C([H])([H])C([H])([H])N([H])/C(=N/[H])/N([H])[H])N([H])C([C@]1([H])C([H])([H])C([H])([H])C([H])([H])N1C([C@]([H])(C([H])([H])C([H])([H])C([H])([H])N([H])/C(=N/[H])/N([H])[H])N([H])C([C@]([H])(C([H])([H])C([H])([H])C(N([H])[H])=O)N([H])C([C@]([H])(C([H])([H])C([H])([H])C([H])([H])N([H])/C(=N/[H])/N([H])[H])N([H])C([C@]([H])(C([H])([H])C([H])([H])C([H])([H])N([H])/C(=N/[H])/N([H])[H])N([H])C([C@]([H])(C([H])([H])C1C([H])=C([H])C([H])=C([H])C=1[H])N([H])C([C@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])N([H])[H])=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

InChI

1S/C96H156N34O20S/c1-55(2)47-67(83(140)127-71(53-131)86(143)125-69(50-58-51-109-54-115-58)85(142)116-60(26-11-13-38-98)78(135)114-52-76(133)128-43-18-31-72(128)87(144)122-66(36-46-151-3)91(148)130-45-20-33-74(130)89(146)126-70(92(149)150)49-57-23-8-5-9-24-57)124-81(138)63(29-16-41-112-95(105)106)120-88(145)73-32-19-44-129(73)90(147)65(30-17-42-113-96(107)108)121-82(139)64(34-35-75(100)132)119-80(137)61(27-14-39-110-93(101)102)117-79(136)62(28-15-40-111-94(103)104)118-84(141)68(48-56-21-6-4-7-22-56)123-77(134)59(99)25-10-12-37-97/h4-9,21-24,51,54-55,59-74,131H,10-20,25-50,52-53,97-99H2,1-3H3,(H2,100,132)(H,109,115)(H,114,135)(H,116,142)(H,117,136)(H,118,141)(H,119,137)(H,120,145)(H,121,139)(H,122,144)(H,123,134)(H,124,138)(H,125,143)(H,126,146)(H,127,140)(H,149,150)(H4,101,102,110)(H4,103,104,111)(H4,105,106,112)(H4,107,108,113)/t59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-/m0/s1

InChIKey

SVWSKJCJNAIKNH-MJZUAXFLSA-N

LogP

4.58470

Topological Polar Surface Area

894.1900000000004 Å²

Hydrogen Bond Donor/Acceptor

40 / 54

Complexity

4500

Synonyms & References

English

Apelin-17 (huMan, bovine, Mouse, rat) Apelin Precursor (61-77) (huMan, bovine, Mouse, rat), Preproapelin (61-77) (huMan, bovine, Mouse, rat)
Apelin Precursor (61-77) (huMan, bovine, Mouse, rat), Preproapelin (61-77) (huMan, bovine, Mouse, rat)
Apelin-17 (human, bovine, mouse, rat),Apelin Precursor (61-77)
H-LYS-PHE-ARG-ARG-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH TRIFLUOROACETATE
APELIN-17 (HUMAN, BOVINE, MOUSE, RAT) TRIFLUOROACETATE
APELIN PRECURSOR (61-77) (HUMAN, BOVINE, MOUSE, RAT) TRIFLUOROACETATE
PREPROAPELIN (61-77) (HUMAN, BOVINE, MOUSE, RAT) TRIFLUOROACETATE
Apelin-17 (human, bovine, mouse, rat) trifluoroacetate salt H-Lys-Phe-Arg-Arg-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH trifluoroacetate salt
L-Phenylalanine,L-lysyl-L-phenylalanyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-
Apelin-17 (human,bovine, mouse, rat),Apelin Precursor (61-77)
APELIN-17 (HUMAN, BOVINE)
Apelin-17 (human, bovine, mouse, rat)
L-Phenylalanine,L-lysyl-L-phenylalanyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histi
H-Lys-Phe-Arg-Arg-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
Apelin-17(human, bovine)

MDL Number

MFCD02179661

FAQ

What regulatory guidelines apply to Apelin-17 (human, bovine) (CAS: 217082-57-0)?

Apelin-17 (human, bovine) (CAS: 217082-57-0) falls under various regulatory frameworks including GHS (Global Harmonized System of Classification and Labelling of Chemicals) for hazardous materials. It is also subject to REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) in the EU, which mandates notification and safety data sheets. FDA regulations govern its use in the US, particularly in pharmaceutical applications. EPA guidelines apply if it is used in environmental or agricultural settings.

Are there alternatives to Apelin-17 (human, bovine) (CAS: 217082-57-0) in synthesis?

For synthesizing peptides like Apelin-17 (human, bovine) (CAS: 217082-57-0), chemists often explore alternatives such as Apelin-3, which is a shorter peptide with similar effects but is easier to synthesize. Other options include using isomers or analogs like Apelin-13, which can be used as intermediates or as standalone compounds depending on the application.

What is the market or research trend for Apelin-17 (human, bovine) (CAS: 217082-57-0)?

The market for Apelin-17 (human, bovine) (CAS: 217082-57-0) is growing with increasing interest in its potential therapeutic applications, particularly in cardiovascular diseases and obesity. Research trends include the development of more potent and selective analogs, as well as exploring its use in combination therapies. The trend also shows a focus on optimizing production methods and reducing costs for broader clinical applications.

How should waste containing Apelin-17 (human, bovine) (CAS: 217082-57-0) be handled?

Waste containing Apelin-17 (human, bovine) (CAS: 217082-57-0) should be collected in appropriate containers and labeled according to hazardous waste regulations. Proper disposal methods include incineration or professional waste disposal services. Environmental protection measures should include minimizing the release of waste into the environment and ensuring safe transportation to disposal facilities, adhering to local and international environmental protection guidelines.