Diethyl propylmalonate

Basic Information

View in Editor

CAS Number

2163-48-6

Molecular Formula

C10H18O4

Molecular Weight

202.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Boiling Point

222°C

Solubility

Soluble in Dichloromethane, Ethanol and Ethyl Acetate.

Refractive Index

n20/D 1.418(lit.)

SMILES

View in Editor

CCCC(C(=O)OCC)C(=O)OCC

InChI

InChI=1S/C10H18O4/c1-4-7-8(9(11)13-5-2)10(12)14-6-3/h8H,4-7H2,1-3H3

InChIKey

GRRSDGHTSMJICM-UHFFFAOYSA-N

LogP

1.5289000000000001

Topological Polar Surface Area

52.60000000000001 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

171

Safety Information

View Safety Information

GHS Hazard Pictograms

H227

Hazard Statement

H227 Combustible liquid
Flammable liquids

Synonyms & References

English

MFCD00009168
2-propyl-malonic acid diethyl ester
NS00026926
EINECS 218-492-2
NSC-53659
FT-0624906
D4708
CS-W015505
2163-48-6
Malonic acid, propyl-, diethyl ester
H10669
Diethyl propylmalonate, 99%
EN300-52603
Z756390284
W-107537
diethyl propyl-malonate
AKOS002710272
DTXSID60176018
Diethyl-n-propylmalonate
AS-14714
Diethyl 2-propylmalonate
Diethyl prop-1-ylmalonate
AM20090197
SCHEMBL31610
Diethyl 2-propylmalonate #
diethyl 2-propylpropanedioate
Q63393654
2-propyl-propanedioic acid diethyl ester
GRRSDGHTSMJICM-UHFFFAOYSA-
1,3-diethyl 2-propylpropanedioate
Propanedioic acid, propyl-, diethyl ester

MDL Number

MFCD00009168

Customs Code

2917190090

FAQ

What regulatory guidelines apply to Diethyl propylmalonate (CAS: 2163-48-6)?

Diethyl propylmalonate (CAS: 2163-48-6) falls under the jurisdiction of several regulatory guidelines. It is classified under the GHS system as a combustible liquid. In the EU, it is regulated under REACH, requiring suppliers to provide safety data sheets (SDS) and register with the European Chemicals Agency (ECHA). For the US market, the FDA and EPA have specific guidelines for the handling and use of chemicals in pharmaceutical and industrial applications.

Are there alternatives to Diethyl propylmalonate (CAS: 2163-48-6) in synthesis?

There are alternative reagents that can be used in synthesis as substitutes for Diethyl propylmalonate (CAS: 2163-48-6). Common alternatives include ethyl propylmalonate and other propionic acid derivatives. These alternatives can offer similar functionalities but with different reactivity profiles, making them suitable for various synthesis pathways depending on the specific application.

What is the market or research trend for Diethyl propylmalonate (CAS: 2163-48-6)?

The market for Diethyl propylmalonate (CAS: 2163-48-6) is steadily growing, driven by its applications in the pharmaceutical and agrochemical industries. Research trends indicate increasing interest in the development of novel derivatives and the exploration of its use in catalytic reactions and as a precursor in organic synthesis. The trend is also toward more sustainable and environmentally friendly production methods.

How should waste containing Diethyl propylmalonate (CAS: 2163-48-6) be handled?

Waste containing Diethyl propylmalonate (CAS: 2163-48-6) should be handled in accordance with local regulations and best practices. Collect all waste in appropriate containers and ensure proper labeling. Incineration is a common method for disposal, but professional waste disposal services should be utilized. Environmental protection precautions include neutralizing acidic or basic waste and ensuring that all waste is treated to minimize environmental impact.