N,N'-Bis(2,6-diisopropylphenyl)carbodiimide

Basic Information

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CAS Number

2162-74-5

Molecular Formula

C25H34N2

Molecular Weight

362.56 g/mol

Chemical Classification

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Powder

Melting Point

50.0 to 54.0 deg-C

Boiling Point

477.7℃ at 760 mmHg

Density

0.9700

Flash Point

197℃

Refractive Index

1.528

SMILES

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CC(C)C1=C(C(=CC=C1)C(C)C)N=C=NC2=C(C=CC=C2C(C)C)C(C)C

InChI

InChI=1S/C25H34N2/c1-16(2)20-11-9-12-21(17(3)4)24(20)26-15-27-25-22(18(5)6)13-10-14-23(25)19(7)8/h9-14,16-19H,1-8H3

InChIKey

XLDBGFGREOMWSL-UHFFFAOYSA-N

LogP

8.317300000000005

Topological Polar Surface Area

24.72 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

419

Safety Information

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GHS Hazard Pictograms

H301

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

AKOS015915473
BIS(2,6-DIISOPROPYLPHENYL)-CARBODIIMIDE
NS00007917
Bis(2,6-diisopropylphenyl)carbodiimide
N,N'-Methanetetraylbis(2,6-bis(1-methylethyl)benzenamine)
EINECS 218-487-5
N-{N-[2,6-bis(propan-2-yl)phenyl]carboximidoyl}-2,6-bis(propan-2-yl)aniline
AMY10377
XLDBGFGREOMWSL-UHFFFAOYSA-N
O12007
N,N/'-bis[2,6-di(propan-2-yl)phenyl]methanediimine
FT-0654584
B2756
SCHEMBL134760
W-109755
2162-74-5
bis(2,6-di-2-propylphenyl)carbodiimide
C25H34N2
(2,6-diisopropylphenyl)carbodiimide
Staboxol 1
2,2',6,6'-Tetraisopropyldiphenylcarbodiimide
Q27894368
Carbodiimide, bis(2,6-diisopropylphenyl)-
MFCD00082211
EC 218-487-5
SY035749
YPK27Z98PL
N,N'-bis[2,6-di(propan-2-yl)phenyl]methanediimine
HMS553G24
Benzenamine, N,N'-methanetetraylbis(2,6-bis(1-methylethyl)-
EN300-256163

MDL Number

MFCD00082211

Customs Code

2921590090

FAQ

What is N,N'-Bis(2,6-diisopropylphenyl)carbodiimide (CAS: 2162-74-5)?

N,N'-Bis(2,6-diisopropylphenyl)carbodiimide (CAS: 2162-74-5) is a carbodiimide derivative with the chemical formula C28H38N2O. It is a white crystalline solid known for its strong coupling capabilities in organic chemistry, commonly used to activate carboxylic acids for amide bond formation. Its structure features two 2,6-diisopropylphenyl groups attached to a central carbodiimide moiety, enhancing reactivity and stability in synthetic applications.

What are the main uses of N,N'-Bis(2,6-diisopropylphenyl)carbodiimide (CAS: 2162-74-5)?

N,N'-Bis(2,6-diisopropylphenyl)carbodiimide (CAS: 2162-74-5) is primarily used as a coupling agent in pharmaceuticals and research for synthesizing peptides and amides. It also serves in industrial applications such as polymer crosslinking and drug development. Its ability to form stable intermediates makes it valuable in organic synthesis, particularly in reactions requiring efficient acylation or amidation processes.

Is N,N'-Bis(2,6-diisopropylphenyl)carbodiimide (CAS: 2162-74-5) safe?

N,N'-Bis(2,6-diisopropylphenyl)carbodiimide (CAS: 2162-74-5) is considered hazardous and requires careful handling. It may cause skin and eye irritation, and inhalation or ingestion can pose health risks. Safety standards recommend using personal protective equipment (PPE), proper ventilation, and avoiding direct contact. Always follow OSHA guidelines and consult safety data sheets (SDS) for specific precautions.

How should N,N'-Bis(2,6-diisopropylphenyl)carbodiimide (CAS: 2162-74-5) be stored?

Store N,N'-Bis(2,6-diisopropylphenyl)carbodiimide (CAS: 2162-74-5) in a cool, dry place away from moisture and light. Keep it in a sealed, airtight container made of glass or polyethylene. Ensure storage at temperatures below 25°C and avoid exposure to air to maintain stability. Always store in a well-ventilated area to prevent potential hazards.