N'-Nitro-L-Arginine

Basic Information

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CAS Number

2149-70-4

Molecular Formula

C6H13N5O4

Molecular Weight

219.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Melting Point

257 ºC (dec.)

Boiling Point

462.4℃ at 760 mmHg

Refractive Index

1.8000 (estimate)

Specific Rotation

23.5 º (c=4, 2N HCl 24 ºC)

SMILES

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C(CC(C(=O)O)N)CN=C(N)N[N+](=O)[O-]

InChI

InChI=1S/C6H13N5O4/c7-4(5(12)13)2-1-3-9-6(8)10-11(14)15/h4H,1-3,7H2,(H,12,13)(H3,8,9,10)/t4-/m0/s1

InChIKey

MRAUNPAHJZDYCK-BYPYZUCNSA-N

LogP

0.58920

Complexity

261

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

DB04223
L-NNA
NG -nitro-L-arginine
BCP19702
N~5~-(N-nitrocarbamimidoyl)-L-ornithine
NSC 53662
7O8V7H6P2J
LP00818
IDI1_001016
(2S)-2-amino-5-[[amino(nitramido)methylene]amino]pentanoic acid
L-N-Nitroarginine
n'-nitro-l-arginine
Q7041453
DTXSID2042696
EINECS 218-418-9
Ornithine, N(5)-(nitroamidino)-, L-
nw-nitro-l-arginine
Spectrum3_001083
AKOS005175145
N (g)-NITRO-L-ARGININE
M03121
Z2768168371
L-NG-nitroarginine
Tocris-0664
AI3-62168
compound 2 [PMID: 9667974]
N(G)-Nitroarginine
EN300-204408
hDDAH inhibitor, 2g
Norvaline, 5-(2-nitroguanidino)-, (+)-
Tox21_500818

MDL Number

MFCD00007033

FAQ

What is N'-Nitro-L-Arginine (CAS: 2149-70-4)?

N'-Nitro-L-Arginine (CAS: 2149-70-4) is a chemical compound derived from L-arginine, featuring a nitro group (-NO2) attached to the N' position. Its molecular formula is C6H12N4O3, and it is typically a white crystalline solid. It exhibits solubility in water and is known for its role as a nitric oxide (NO) donor in biological systems, making it relevant in pharmaceutical and research contexts.

What are the main uses of N'-Nitro-L-Arginine (CAS: 2149-70-4)?

N'-Nitro-L-Arginine (CAS: 2149-70-4) is primarily used in pharmaceutical research as a precursor for nitric oxide-releasing compounds. It also serves as an intermediate in chemical synthesis and is studied for its potential applications in cardiovascular and metabolic research. Its use in industrial and food sectors is limited, with focus on controlled laboratory environments.

Is N'-Nitro-L-Arginine (CAS: 2149-70-4) safe?

N'-Nitro-L-Arginine (CAS: 2149-70-4) requires careful handling due to its potential reactivity and hazard classification. Safety data sheets indicate it may pose risks under specific conditions, such as exposure to heat or ignition sources. Protective measures include wearing gloves, goggles, and ensuring proper ventilation. Adherence to chemical safety standards is essential for safe use and storage.

How should N'-Nitro-L-Arginine (CAS: 2149-70-4) be stored?

N'-Nitro-L-Arginine (CAS: 2149-70-4) should be stored in a cool, dry, and dark place, ideally at 2-8°C. It requires airtight containers to prevent moisture absorption and degradation. Avoid exposure to incompatible substances and ensure storage areas are well-ventilated to maintain stability and safety.