N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-quinolinyl)-D-alanine | CAS No. 214852-58-1
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-quinolinyl)-D-alanine
Basic Information
CAS Number
214852-58-1
Molecular Formula
C27H22N2O4
Molecular Weight
438.48 g/mol
AD
Chemical Classification
Basic Physical Properties
Solubility
Insuluble (5.7E-4 g/L) (25 ºC),
Synonyms & References
English
- MFCD01318746
- 214852-58-1
- Fmoc-D-Ala(2-Qui)-OH
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(quinolin-2-yl)propanoic acid
- DTXSID601145308
- (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-quinolin-2-ylpropanoic acid
- Fmoc-3-(2'-quinolyl)-D-alanine
- (alphaR)-alpha-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-quinolinepropanoic acid
- Fmoc-beta-(2-quinolyl)-d-ala-oh
- CHEMBL4285388
- Fmoc--(2-quinolyl)-D-Ala-OH
- E70575
- A903012
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(quinolin-2-yl)propanoic acid
- S-214852-58-1
- Fmoc-beta-(2-quinolyl)-D-Ala-OH, AldrichCPR
- J-014098
- BDBM50467856
- 2-Quinolinepropanoicacid, a-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-,(aR)-
- Fmoc-b-(2-quinolyl)-D-Ala-OH
- Fmoc-D-2-Quinoylalanine
- FMOC-β-(2-QUINOLYL)-D-ALA-OH
- FMoc-beta-(2-quinolyl)-d-ala-oh
- FMOC-D-ALA(2-QUI)-OH
- FMOC-D-ALA(2'-QUINOLYL)-OH
- FMOC-D-QAL(2)-OH
MDL Number
MFCD01318746
FAQ
What are the physical and chemical properties of N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-quinolinyl)-D-alanine (CAS: 214852-58-1)?
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-quinolinyl)-D-alanine (CAS: 214852-58-1) is a crystalline solid with a molecular weight of approximately 461.4 g/mol. It is slightly water-soluble and stable under normal conditions. The compound reacts readily with nucleophiles due to its ester and amide functionalities. It has a high boiling point and is resistant to thermal and oxidative degradation.
How is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-quinolinyl)-D-alanine (CAS: 214852-58-1) typically synthesized?
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-quinolinyl)-D-alanine is typically synthesized through multistep organic reactions, including protected amino acid synthesis and amidation. The key steps involve the formation of a fluorenylmethoxycarbonyl (Fmoc) protected derivative and subsequent coupling with 2-quinolinyl-D-alanine. The reaction is often catalyzed by a suitable coupling reagent such as HATU and performed under anhydrous conditions to ensure high yield and selectivity.
What industries use N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-quinolinyl)-D-alanine (CAS: 214852-58-1)?
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-quinolinyl)-D-alanine (CAS: 214852-58-1) is primarily used in the pharmaceutical industry for the development of new drugs. It is also utilized in the preparation of organic semiconductors and photovoltaic materials. Additionally, it can be employed in the synthesis of complex molecules for research purposes and in the development of advanced sensor technologies.
What precautions should be taken when handling N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-quinolinyl)-D-alanine (CAS: 214852-58-1)?
When handling N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-quinolinyl)-D-alanine (CAS: 214852-58-1), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be conducted in a well-ventilated area or fume hood. Spills should be handled with care using appropriate absorbent materials and should be cleaned up promptly. Always refer to the Safety Data Sheet (SDS) for detailed information on safe handling and storage.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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