N~5~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-ornithine | CAS No. 214750-74-0

N~5~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-ornithine

Basic Information

CAS Number

214750-74-0

Molecular Formula

C24H26N2O6

Molecular Weight

438.48 g/mol

AD

Basic Physical Properties

C=CCOC(=O)NCCCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

InChI

InChI=1S/C24H26N2O6/c1-2-14-31-23(29)25-13-7-12-21(22(27)28)26-24(30)32-15-20-18-10-5-3-8-16(18)17-9-4-6-11-19(17)20/h2-6,8-11,20-21H,1,7,12-15H2,(H,25,29)(H,26,30)(H,27,28)/t21-/m1/s1

InChIKey

RXLIOYNXBHZZBI-OAQYLSRUSA-N

LogP

3.670700000000002

Topological Polar Surface Area

113.96 Ų

Hydrogen Bond Donor/Acceptor

3 / 8

Complexity

647

Synonyms & References

English

  • DS-18383
  • (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-(prop-2-enoxycarbonylamino)pentanoic acid
  • (R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-5-(allyloxycarbonylamino)pentanoic acid
  • Fmoc-D-Orn(Aloc)-OH
  • C24H26N2O6
  • C74042
  • (R)-2-(Fmoc-amino)-5-(Aloc-amino)pentanoic acid
  • (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(((allyloxy)carbonyl)amino)pentanoicacid
  • AKOS016843074
  • SCHEMBL119653
  • N~2~-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-N~5~-{[(prop-2-en-1-yl)oxy]carbonyl}-D-ornithine
  • DTXSID30679804
  • N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-gamma-(allyloxycarbonyl)-D-ornithine (Fmoc-D-Orn(Alloc)-OH)
  • (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(((allyloxy)carbonyl)amino)pentanoic acid
  • N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-gamma-(allyloxycarbonyl)-D-ornithine
  • MFCD00798638
  • CS-0157977
  • (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6--5-(((allyloxy)carbonyl)amino)pentanoic acid
  • 214750-74-0
  • Fmoc-D-Orn(Alloc)-OH
  • N-α-Boc-N-δ-allyloxycarbonyl-D-ornithine
  • AmbotzFAA1491
  • N-Fmoc-N'-allyloxycarbonyl-D-ornithine

MDL Number

MFCD00798638

FAQ

What are the physical and chemical properties of N~5~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-ornithine (CAS: 214750-74-0)?

N~5~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-ornithine is a white crystalline powder with a molecular weight of approximately 600 g/mol. It has good solubility in organic solvents like dichloromethane and poor solubility in water. This compound is reactive and can undergo hydrolysis under basic conditions.

How is N~5~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-ornithine (CAS: 214750-74-0) typically synthesized?

N~5~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-ornithine is synthesized via multistep processes involving protection of the ornithine amine, introduction of the allyloxy and fluoren-9-ylmethoxy carbonyl groups, and subsequent deprotection. Common solvents include dichloromethane and pyridine. The yield and purity of the final product can be up to 85%.

What industries use N~5~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-ornithine (CAS: 214750-74-0)?

N~5~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-ornithine finds applications in pharmaceuticals for the synthesis of bioactive compounds and in polymers for its potential as a monomer. It is also used in the development of sensors and semiconductors due to its chemical versatility.

What precautions should be taken when handling N~5~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-ornithine (CAS: 214750-74-0)?

When handling N~5~-[(Allyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-ornithine, use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be handled with caution; use appropriate absorbents and dispose of waste according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.

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