Clindamycin HCl (Clindamycin Phosphate EP Impurity E HCl)

Basic Information

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CAS Number

21462-39-5

Molecular Formula

C18H34Cl2N2O5S

Molecular Weight

461.45 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

141 ºC

Boiling Point

628.1°C at 760 mmHg

Flash Point

345.1 °C

Solubility

H2O: 50 mg/mL, clear, colorless

Refractive Index

143 ° (C=2, H2O)

Specific Rotation

+142.0° - +151.0° (c=2, H2O)

SMILES

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CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)Cl.Cl

InChI

InChI=1S/C18H33ClN2O5S.ClH/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H/t9-,10+,11-,12+,13-,14+,15+,16+,18+;/m0./s1

InChIKey

AUODDLQVRAJAJM-XJQDNNTCSA-N

LogP

0.8113000000000001

Topological Polar Surface Area

102.26000000000002 Å²

Hydrogen Bond Donor/Acceptor

4 / 7

Complexity

502

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

UNII-T20OQ1YN1W
Clindamycin hydrochloride monohydrate
NSC-756696
CLINDAMYCIN HYDROCHLORIDE [MI]
U 21251F
Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside monohydrochloride
AMY33461
NS00076311
Clindamycin hydrochloride, lincosamide antibiotic
21462-39-5
Clindamycin hydrochloride (JP17/USP)
CLINDAMYCIN HYDROCHLORIDE [USP MONOGRAPH]
Clindamycin hydrochloride (USP:BAN:JAN)
L-THREO-.ALPHA.-D-GALACTO-OCTOPYRANOSIDE, METHYL 7-CHLORO-6,7,8-TRIDEOXY-6-(((1-METHYL-4-PROPYL-2-PYRROLIDINYL)CARBONYL)AMINO)-1-THIO-,(2S-TRANS)-, MONOHYDROCHLORIDE
Clindamycin hydrochloride
CLINDAMYCIN HYDROCHLORIDE [MART.]
(2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;hydrochloride
NSC 756696
(4R)-N-[(1S,2S)-2-chloro-1-[(3R,4R,6R)-3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl]propyl]-1-methyl-4-propyl-pyrrolidine-2-carboxamide hydrochloride;Clindamycin hydrochloride
58207-19-5
(7S)-7-Chloro-7-deoxylincomycin hydrochloride
L-threo-alpha-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-((((2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-, monohydrochloride
L-threo-alpha-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(((1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-, (2S-trans)-, monohydrochloride
ZydaClin
Sobelin
(2S,4R)-N-((1S,2S)-2-CHLORO-1-((2R,3R,4S,5R,6R)-3,4,5-TRIHYDROXY-6-(METHYLTHIO)TETRAHYDRO-2H-PYRAN-2-YL)PROPYL)-1-METHYL-4-PROPYLPYRROLIDINE-2-CARBOXAMIDE HYDROCHLORIDE
Antirobe vet.
Clindamycin HCl (Dalacin)
Clindamycin 1000 microg/mL in Acetonitrile
D02132
CAS-21462-39-5