Methyl 2-amino-4-(3-chloropropoxy)-5-methoxybenzoate | CAS No. 214470-59-4

Methyl 2-amino-4-(3-chloropropoxy)-5-methoxybenzoate

Basic Information

CAS Number

214470-59-4

Molecular Formula

C12H16ClNO4

Molecular Weight

273.72 g/mol

AD

Basic Physical Properties

COC1=C(C=C(C(=C1)C(=O)OC)N)OCCCCl

InChI

InChI=1S/C12H16ClNO4/c1-16-10-6-8(12(15)17-2)9(14)7-11(10)18-5-3-4-13/h6-7H,3-5,14H2,1-2H3

InChIKey

MWAMTEYWDWYKQO-UHFFFAOYSA-N

LogP

2.0717

Topological Polar Surface Area

70.78 Ų

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

265

Synonyms & References

English

  • 2-aMino-4-(3-chloropropoxy)-5-Methoxybenzoate
  • 2-amino-4-(3-chloropropoxy)-5-methoxy-benzoic acid methyl ester
  • 2-amino-4-(3-chloro-propoxy)-5-methoxy-benzoic acid methyl ester
  • methyl 2-amino-4-(3-chloropropoxy)-5-methoxybenzoate
  • methyl 5-methoxy-4-(3-chloropropoxy)anthranilate
  • AS-72104
  • CS-0061903
  • 2-Amino-4-(3-chloro-propoxy)-5-methoxy-benzoic acid methyl ester
  • AKOS030525448
  • 214470-59-4
  • W17344
  • methyl2-amino-4-(3-chloropropoxy)-5-methoxybenzoate
  • SCHEMBL1011427
  • A900894
  • MWAMTEYWDWYKQO-UHFFFAOYSA-N
  • SY233327
  • methyl 5-methoxy-4-(3-chloropropoxy)-anthranilate
  • MFCD20266170
  • Benzoic acid, 2-amino-4-(3-chloropropoxy)-5-methoxy-, methyl ester

MDL Number

MFCD20266170

FAQ

What are the physical and chemical properties of Methyl 2-amino-4-(3-chloropropoxy)-5-methoxybenzoate (CAS: 214470-59-4)?

Methyl 2-amino-4-(3-chloropropoxy)-5-methoxybenzoate (CAS: 214470-59-4) is a crystalline compound with a molecular weight of approximately 347.02 g/mol. It has limited water solubility but is soluble in organic solvents like acetone and dimethylformamide. This compound exhibits moderate reactivity, particularly in nucleophilic substitution reactions. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

How is Methyl 2-amino-4-(3-chloropropoxy)-5-methoxybenzoate (CAS: 214470-59-4) typically synthesized?

Methyl 2-amino-4-(3-chloropropoxy)-5-methoxybenzoate (CAS: 214470-59-4) is typically synthesized via a multi-step process involving the reaction of 4-(3-chloropropoxy)-5-methoxybenzoic acid with methyl amine. This reaction is catalyzed by a mild base such as triethylamine, and the product is isolated by crystallization from organic solvents. The yield is around 75-80%, and the process is known for its good selectivity.

What industries use Methyl 2-amino-4-(3-chloropropoxy)-5-methoxybenzoate (CAS: 214470-59-4)?

Methyl 2-amino-4-(3-chloropropoxy)-5-methoxybenzoate (CAS: 214470-59-4) is used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It also finds applications in the polymer industry for the modification of polymer properties, and in the semiconductor industry for the fabrication of electronic materials. Additionally, it is utilized in the development of new chemical sensors.

What precautions should be taken when handling Methyl 2-amino-4-(3-chloropropoxy)-5-methoxybenzoate (CAS: 214470-59-4)?

When handling Methyl 2-amino-4-(3-chloropropoxy)-5-methoxybenzoate (CAS: 214470-59-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. For detailed safety information, refer to the Safety Data Sheet (SDS) available from your supplier.

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