Mono-poc tenofovir

Basic Information

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CAS Number

211364-69-1

Molecular Formula

C14H22N5O7P

Molecular Weight

403.33 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Insecticides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

303-305°C (dec.)

SMILES

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CC(C)OC(=O)OCOP(=O)(COC(C)CN1C=NC2=C(N=CN=C21)N)O

InChI

InChI=1S/C14H22N5O7P/c1-9(2)26-14(20)23-7-25-27(21,22)8-24-10(3)4-19-6-18-11-12(15)16-5-17-13(11)19/h5-6,9-10H,4,7-8H2,1-3H3,(H,21,22)(H2,15,16,17)

InChIKey

XLYSRKLPLHUWCJ-UHFFFAOYSA-N

LogP

1.4921999999999997

Topological Polar Surface Area

160.91 Å²

Hydrogen Bond Donor/Acceptor

3 / 12

Complexity

540

Synonyms & References

English

Mono-POC Tenofovir
Mono-POC Tenofovir (Mixture of Diastereomers)
[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphinic acid
Mono-POC Tenofovir (Mixture of Diastereomers)
Tenofovir Monoisoproxil
(8R)-9-(6-Amino-9H-purin-9-yl)-5-hydroxy-8-methyl-2,4,7-trioxa-5-phosphanonanoic acid 1-methylethyl ester 5-oxide
Tenofovir disoproxil fumarate impurity A [WHO-IP]
2,4,7-Trioxa-5-phosphanonanoic acid, 9-(6-amino-9H-purin-9-yl)-5-hydroxy-8-methyl-, 1-methylethyl ester, 5-oxide, (8R)-
((((((R)-1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(hydroxy)phosphoryl)oxy)methyl isopropyl carbonate
2,4,7-Trioxa-5-phosphanonanoic acid, 9-(6-amino-9H-purin-9-yl)-5-hydroxy-8-methyl-, 1-methylethyl ester, 5-oxide, (8R)-; Tenofovir monoisoproxil
UNII-ZKS5H56W6A
SCHEMBL14507066
CHEMBL3040036
Tenofovir disoproxil impurity E
Tenofovir isoproxil monoester
({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)({[(propan-2-yloxy)carbonyl]oxy}methoxy)phosphinic acid
ZKS5H56W6A
DTXSID20718877
((((r)-1-(6-amino-9h-purin-9-yl)propan-2-yl)oxymethyl)(hydroxy)phosphoryloxy)methyl isopropyl carbonate
({[(Propan-2-yl)oxy]carbonyl}oxy)methyl hydrogen ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate
211364-69-1
MONO-POC TENOFOVIR
((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(hydroxy)phosphoryl)oxy)methyl isopropyl carbonate

MDL Number

MFCD22683724

FAQ

What regulatory guidelines apply to Mono-poc tenofovir (CAS: 211364-69-1)?

Mono-poc tenofovir (CAS: 211364-69-1) is subject to various regulatory guidelines including the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH registration for European manufacturers, and FDA/EPA requirements for pharmaceutical use. Compliance with these regulations is necessary for safe handling, storage, and distribution.

Are there alternatives to Mono-poc tenofovir (CAS: 211364-69-1) in synthesis?

Alternatives to Mono-poc tenofovir (CAS: 211364-69-1) in synthesis include other antiretroviral agents such as tenofovir disoproxil fumarate and tenofovir alafenamide, which may offer similar antiviral activity with different chemical structures and synthesis routes.

What is the market or research trend for Mono-poc tenofovir (CAS: 211364-69-1)?

The market for Mono-poc tenofovir (CAS: 211364-69-1) shows increasing demand as it is a key component in antiretroviral therapy for HIV. Research trends focus on its efficacy, safety, and potential in combination therapies, as well as the development of more stable and bioavailable forms.

How should waste containing Mono-poc tenofovir (CAS: 211364-69-1) be handled?

Waste containing Mono-poc tenofovir (CAS: 211364-69-1) should be collected in appropriate containers, labeled with the correct hazardous waste symbols, and disposed of through professional waste disposal services. Proper incineration or chemical treatment methods should be employed to ensure environmental safety and compliance with local regulations.