1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine

Basic Information

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CAS Number

210880-92-5

Molecular Formula

C6H8ClN5O2S

Molecular Weight

249.68 g/mol

Basic Physical Properties

Melting Point

178.8C

Boiling Point

435.2°Cat760mmHg

Water Solubility

327MG/LAT20C

Flash Point

217°C

Refractive Index

1.709

SMILES

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CNC(NCC1=CN=C(Cl)S1)=N[N+]([O-])=O

InChI

InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11)

InChIKey

PGOOBECODWQEAB-UHFFFAOYSA-N

LogP

1.95820

Complexity

258

Safety Information

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GHS Hazard Pictograms

H302

H410

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H410 Very toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Toxicity

LD50 in rats (mg/kg): >5000 orally; >2000 dermally; LC50 in rats (mg/l): >6.1 inhalation; LC50 in bobwhite quail, mallard duck (ppm): >5200, >5200 (dietary); LC50 (96 hr) in rainbow trout, bluegill (mg/l): >100, >120 (Ohkawara)

Synonyms & References

English

Clothianidin
(E)-1-(2-Chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine
1-(2-Chloro-5-thiazolylmethyl)-3-methyl-2-nitroguanidine
3-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-1-nitro-guanidine
Potassiumborate
(E)-1-(2-chlorothiazol-5-ylmethyl)-3-methyl-2-nitroguanidine
1-(2-chlorothiazol-5-ylmethyl)-2-nitro-3-methyl-guanidine
1-[(2-chloro-5-thiazolyl)methyl]-3-methyl-2-nitroguanidine
3-(2-chloro-5-thiazolylmethyl)-1-methyl-2-nitroguanidine
Apacz
Belay
Celero
Clutch
Dantop
Dantotsu
N-(2-chloro-5-thiazolylmethyl)-3-methyl-2-nitro-guanidine
Pancho
Poncho
TI 435

MDL Number

MFCD06200753

Customs Code

2934100016

FAQ

What is 1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine (CAS: 210880-92-5)?

1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine, with CAS number 210880-92-5, is a nitrogen-containing organic compound. It features a guanidine group attached to a 2-chloro-1,3-thiazole ring, making it a versatile intermediate in chemical synthesis. The compound is known for its stability and reactivity, commonly used in the development of pharmaceuticals and agrochemicals.

What are the main uses of 1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine (CAS: 210880-92-5)?

This compound is primarily used in the pharmaceutical industry for the synthesis of various drugs, particularly those targeting inflammatory and infectious diseases. It also finds applications in agrochemicals, as a component in pesticides and herbicides. Additionally, it is used in research for developing new compounds and in industrial processes for chemical intermediates.

Is 1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine (CAS: 210880-92-5) safe?

While 1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine is generally considered safe when handled properly, it may pose risks if exposed to high temperatures or incompatible substances. Safety precautions include wearing appropriate personal protective equipment (PPE), ensuring proper ventilation, and following standard chemical handling protocols. It is important to adhere to safety guidelines to minimize potential hazards.

How should 1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine (CAS: 210880-92-5) be stored?

1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine should be stored in a cool, dry, and well-ventilated area, away from direct light. It is best kept in a sealed container at a temperature below 25°C and in a humidity-controlled environment to maintain stability. Avoid exposure to moisture and incompatible materials to ensure safe storage.