Neflamapimod | CAS No. 209410-46-8

Neflamapimod

Basic Information

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CAS Number

209410-46-8

Molecular Formula

C19H9Cl2F2N3OS

Molecular Weight

436.3 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Boiling Point

578.9°Cat760mmHg

Density

1.55

Flash Point

303.9°C

Refractive Index

1.692

SMILES

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C1=CC(=C(C(=C1)Cl)C2=C3C=CC(=NN3C=NC2=O)SC4=C(C=C(C=C4)F)F)Cl

InChI

InChI=1S/C19H9Cl2F2N3OS/c20-11-2-1-3-12(21)17(11)18-14-5-7-16(25-26(14)9-24-19(18)27)28-15-6-4-10(22)8-13(15)23/h1-9H

InChIKey

VEPKQEUBKLEPRA-UHFFFAOYSA-N

LogP

5.492700000000002

Topological Polar Surface Area

47.260000000000005 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

762

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

D10959
VD-31745
CCG-269082
BCPP000015
NCGC00241111-12
J-013730
5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)thio]-6-pyrimido[1,6-b]pyridazinone
5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido[1,6-b]pyridazin-6-one
NCGC00241111-02
Q27089208
VRT-031745
5-(2,6-Dichlorophenyl)-2-[2,4-difluorophenyl)thio]-6H-pyrimido[1,6-b]pyridazin-6-one
AC-707
5-(2,6-dichlorophenyl)-2-(2,4-difluorophenylsulfanyl)-6h-pyrimido[3,4-b]pyridazin-6-one
DTXSID90175115
HMS3654L10
5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)thio]pyrimido[1,6-b]pyridazin-6-one
NS00070857
NSC-785334
C19H9Cl2F2N3OS
SB19425
NEFLAMAPIMOD [INN]
TYL52QM320
AM84727
hexadecylacrylate
EX-8451
5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)-thio)-6H-pyrimido[1,6-b]pyridazin-6-one
VX 745
NCGC00241111-01
NEFLAMAPIMOD [WHO-DD]
SCHEMBL156367

MDL Number

MFCD09834070

Customs Code

2933990090

FAQ

What is Neflamapimod (CAS: 209410-46-8)?

Neflamapimod is an inhibitor of p38 mitogen-activated protein kinase (MAPK), used primarily in preclinical research. It has potential therapeutic applications in inflammation and cancer research.

What are the main uses of Neflamapimod (CAS: 209410-46-8)?

Neflamapimod is mainly used for research purposes, particularly in studies related to inflammation and cancer. It is also used in preclinical drug development.

Is Neflamapimod (CAS: 209410-46-8) safe?

Neflamapimod is generally considered safe for laboratory use under proper handling conditions. However, it should be used with caution, and appropriate safety measures should be followed to prevent skin contact and inhalation.

How should Neflamapimod (CAS: 209410-46-8) be stored?

Neflamapimod should be stored in a cool, dry place, away from direct sunlight and heat sources. Maintain a temperature below 25°C and store in a tightly closed container to protect from humidity and light exposure.