4-Chloro-1H-indazol-3-amine

Basic Information

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CAS Number

20925-60-4

Molecular Formula

C7H6ClN3

Molecular Weight

167.6 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

159-162

Boiling Point

408.7°C at 760 mmHg

Density

1.533

Flash Point

201°C

Refractive Index

1.777

SMILES

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C1=CC2=C(C(=C1)Cl)C(=NN2)N

InChI

InChI=1S/C7H6ClN3/c8-4-2-1-3-5-6(4)7(9)11-10-5/h1-3H,(H3,9,10,11)

InChIKey

QPLXQNVPEHUPTR-UHFFFAOYSA-N

LogP

1.7984999999999993

Topological Polar Surface Area

54.7 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

153

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

SR-01000644010-1
CS-W022128
CCG-54953
AKOS005069351
1H-Indazol-3-amine, 4-chloro-
AM20060980
NSC-227386
4-chloranyl-1~{H}-indazol-3-amine
SB16283
EQT
4-chloro-1H-indazole-3-amine
4-Chloro-2h-indazol-3-ylamine
3-Amino-4-chloro-1H-indazole
BCP27217
DTXSID80310477
QPLXQNVPEHUPTR-UHFFFAOYSA-N
MFCD00663139
20925-60-4
AE-413/25046009
Oprea1_798817
CHEMBL1333961
4-chloro-1H-indazol-3-amine
CHEBI:183661
A15366
SMR000457601
3-amino-4-chloroindazole
3-amino4-chloroindazole
NSC227386
10Y-0704
4-chloro-1H-indazol-3-ylamine
1H-Indazol-3-amine, 4-chloro

MDL Number

MFCD00663139

Customs Code

2933990090

FAQ

What regulatory guidelines apply to 4-Chloro-1H-indazol-3-amine (CAS: 20925-60-4)?

4-Chloro-1H-indazol-3-amine (CAS: 20925-60-4) is classified as a hazardous chemical under the GHS (Globally Harmonized System of Classification and Labeling of Chemicals). It falls under the category of organic compounds with potential health and environmental hazards. In the EU, it is regulated under REACH (Registration, Evaluation, Authorization and Restriction of Chemicals). The FDA and EPA may have specific requirements regarding its use and handling in the United States. Proper labeling, storage, and disposal practices are essential to comply with these regulations.

Are there alternatives to 4-Chloro-1H-indazol-3-amine (CAS: 20925-60-4) in synthesis?

There are several alternatives to 4-Chloro-1H-indazol-3-amine (CAS: 20925-60-4) that can be used in synthesis, such as 4-fluoro-1H-indazol-3-amine, 4-bromo-1H-indazol-3-amine, and 1H-indazol-3-amine. These compounds are often used as analogs in medicinal chemistry and organic synthesis due to their similar structures and potential biological activities. Selecting an alternative depends on the specific application and desired properties.

What is the market or research trend for 4-Chloro-1H-indazol-3-amine (CAS: 20925-60-4)?

The market for 4-Chloro-1H-indazol-3-amine (CAS: 20925-60-4) is driven by its use in pharmaceuticals and agrochemicals due to its potential as an intermediate in the synthesis of medicinal compounds. Research trends indicate an increasing interest in developing new derivatives and analogs of indazolamines for drug discovery. Price trends show fluctuations based on market demand and supply, with emerging research focusing on optimizing synthesis methods and exploring new applications.

How should waste containing 4-Chloro-1H-indazol-3-amine (CAS: 20925-60-4) be handled?

Waste containing 4-Chloro-1H-indazol-3-amine (CAS: 20925-60-4) should be collected in appropriate containers and labeled with the chemical name and CAS number. Proper disposal methods include neutralization to reduce the corrosive nature of the waste and incineration for hazardous waste. Environmental protection measures should be followed to prevent contamination of air, water, and soil. Professional waste disposal services should be utilized to ensure compliance with regulatory requirements and safe disposal practices.