1-(2-Oxetanyl)methanamine

Basic Information

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CAS Number

2091328-57-1

Molecular Formula

C4H9NO

Molecular Weight

87.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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NC[C@@H]1CCO1

InChI

InChI=1S/C4H9NO/c5-3-4-1-2-6-4/h4H,1-3,5H2

InChIKey

QDEFNAHLCTUWAH-UHFFFAOYSA-N

LogP

-0.26600000000000024

Topological Polar Surface Area

35.25 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

46.8

Synonyms & References

English

oxetan-2-ylmethanamine
2-OXETANEMETHANAMINE
C-OXETAN-2-YL-METHYLAMINE
[(2S)-oxetan-2-yl]methanamine
2-AMINOMETHYLOXETANE
(S)-Oxetan-2-ylmethanamine
aminomethyl oxetane
2-Oxetanylmethanamine
Oxetane-2-methanamine
Oxetan-2-ylmethylamine
2-(Aminomethyl)oxetane
1-oxetan-2-ylmethanamine
(S)-Oxetane-2-methanamine
1-(Oxetan-2-yl)methanamine
QDEFNAHLCTUWAH-UHFFFAOYSA-N
BCP30690
FCH947925
ANW-
(S)-C-Oxetan-2-yl-methylamine

MDL Number

MFCD31727897

FAQ

What are the physical and chemical properties of 1-(2-Oxetanyl)methanamine (CAS: 2091328-57-1)?

1-(2-Oxetanyl)methanamine (CAS: 2091328-57-1) is a colorless to slightly yellowish liquid. Its molecular weight is approximately 101.13 g/mol, and it has a solubility of about 10 g/L in water at 25°C. Chemically, it is moderately reactive, especially with strong acids and bases. It can undergo amine substitution reactions and is often used as a precursor in organic synthesis.

How is 1-(2-Oxetanyl)methanamine (CAS: 2091328-57-1) typically synthesized?

1-(2-Oxetanyl)methanamine is typically synthesized via the reaction of 2-oxetanol and methylamine. The process involves nucleophilic substitution, where 2-oxetanol acts as the nucleophile and methylamine as a base. Commonly used solvents include methanol, and the reaction is usually catalyzed by strong bases such as sodium hydride or potassium tert-butoxide. The overall yield can be up to 85%.

What industries use 1-(2-Oxetanyl)methanamine (CAS: 2091328-57-1)?

1-(2-Oxetanyl)methanamine (CAS: 2091328-57-1) finds application in the pharmaceuticals industry for the synthesis of certain drug intermediates. It is also used in the polymer industry as a monomer for the production of specific polymers. Additionally, it has been explored for use in sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 1-(2-Oxetanyl)methanamine (CAS: 2091328-57-1)?

When handling 1-(2-Oxetanyl)methanamine (CAS: 2091328-57-1), it is essential to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Ensure proper ventilation by working in a fume hood. Spills should be cleaned up immediately using appropriate absorbents. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.