Acid-PEG1-C2-Boc

Basic Information

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CAS Number

2086689-08-7

Molecular Formula

C10H18O5

Molecular Weight

218.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

SMILES

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O=C(OC(C)(C)C)CCOCCC(O)=O

InChI

InChI=1S/C10H18O5/c1-10(2,3)15-9(13)5-7-14-6-4-8(11)12/h4-7H2,1-3H3,(H,11,12)

InChIKey

ZDYGOKORAHMWLC-UHFFFAOYSA-N

LogP

1.2095

Topological Polar Surface Area

72.83000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Synonyms & References

English

Acid-PEG1-t-butyl ester

MDL Number

MFCD30723273

FAQ

What are the physical and chemical properties of Acid-PEG1-C2-Boc (CAS: 2086689-08-7)?

Acid-PEG1-C2-Boc (CAS: 2086689-08-7) is a PEGylated derivative with a molecular weight of approximately 441.5 g/mol. It has a crystalline form and exhibits good solubility in polar solvents. This compound is known for its reactivity, particularly in conjugation reactions with proteins and other biomolecules due to its carboxylic acid group.

How is Acid-PEG1-C2-Boc (CAS: 2086689-08-7) typically synthesized?

Acid-PEG1-C2-Boc (CAS: 2086689-08-7) is synthesized by reacting PEG with a carboxylic acid chloride intermediate, followed by Boc deprotection. Commonly, this involves using a carbodiimide coupling agent to activate the carboxylic acid, ensuring high selectivity and yield in the synthesis process.

What industries use Acid-PEG1-C2-Boc (CAS: 2086689-08-7)?

Acid-PEG1-C2-Boc (CAS: 2086689-08-7) is predominantly used in the pharmaceutical and biotechnology industries for drug conjugation and in polymer research. It is also applied in sensor technology and semiconductor manufacturing for functionalization purposes.

What precautions should be taken when handling Acid-PEG1-C2-Boc (CAS: 2086689-08-7)?

When handling Acid-PEG1-C2-Boc (CAS: 2086689-08-7), it is essential to wear appropriate personal protective equipment (PPE), including gloves and goggles. Work should be conducted in a fume hood to minimize inhalation risk. In case of spill, immediately clean up using appropriate materials and follow the safety data sheet (SDS) guidelines for disposal.