4-amino-2-hydroxybenzoic acid, pyridine-4-carbohydrazide

Basic Information

View in Editor

CAS Number

2066-89-9

Molecular Formula

C13H14N4O4

Molecular Weight

290.28 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

142-144°

Boiling Point

380.8°C at 760 mmHg

SMILES

View in Editor

C1=CC(=C(C=C1N)O)C(=O)O.C1=CN=CC=C1C(=O)NN

InChI

InChI=1S/C7H7NO3.C6H7N3O/c8-4-1-2-5(7(10)11)6(9)3-4;7-9-6(10)5-1-3-8-4-2-5/h1-3,9H,8H2,(H,10,11);1-4H,7H2,(H,9,10)

InChIKey

RKPHTRVPGYGVQD-UHFFFAOYSA-N

LogP

0.3576999999999991

Topological Polar Surface Area

151.55999999999997 Å²

Hydrogen Bond Donor/Acceptor

7 / 8

Complexity

280

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

NSC 758447
SBI-0051819.P002
BSPBio_002450
isonicotinic acid hydrazide P-*aminosalicylate
83J17CN0MN
RD 328
SPBio_001971
s4404
NCGC00021150-01
NSC758447
GEWO-399
EINECS 218-183-2
IDI1_000327
isonicotinohydrazide4-amino-2-hydroxybenzoate
SPECTRUM1503381
PAS-HIDRACIDA
NCGC00021150-04
SR-01000000138-2
Isoniazid & p-Aminosalicylic acid
isonicotinohydrazide 4-amino-2-hydroxybenzoate
Pasiniazidum [INN-Latin]
Pharmakon1600-01503381
Spectrum2_001936
Paraniazide;Pasiniazide;Isonicotinic acid hydrazide p-aminosalicylate
KBioGR_001606
4-Pyridinecarboxylic acid hydrazide 4-amino-2-hydroxybenzoate
RD-328
KBio1_000327
NIDRAPAS
NSC-758447
PASINIAZID [INN]

MDL Number

MFCD00079376

Customs Code

2933399090

FAQ

What regulatory guidelines apply to 4-amino-2-hydroxybenzoic acid, pyridine-4-carbohydrazide (CAS: 2066-89-9)?

4-Amino-2-hydroxybenzoic acid, pyridine-4-carbohydrazide (CAS: 2066-89-9) falls under the scope of various regulatory guidelines. It is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) for its physical hazards and health effects. Additionally, it must comply with REACH regulations in the European Union for the registration of chemical substances. In the United States, it also adheres to FDA and EPA guidelines for safe handling and disposal.

Are there alternatives to 4-amino-2-hydroxybenzoic acid, pyridine-4-carbohydrazide (CAS: 2066-89-9) in synthesis?

There are several alternatives to 4-amino-2-hydroxybenzoic acid, pyridine-4-carbohydrazide (CAS: 2066-89-9) that can be used in synthesis, such as related carbohydrazide derivatives or substituted benzoic acid analogs. Common alternative reagents include 2-hydroxybenzohydrazide or 5-amino-2-hydroxybenzoic acid. These alternatives can offer similar functionalities while potentially providing easier synthesis or better reactivity in specific applications.

What is the market or research trend for 4-amino-2-hydroxybenzoic acid, pyridine-4-carbohydrazide (CAS: 2066-89-9)?

The market for 4-amino-2-hydroxybenzoic acid, pyridine-4-carbohydrazide (CAS: 2066-89-9) shows increasing interest in its use as a key intermediate in the pharmaceutical industry, particularly in the development of antiviral and anti-inflammatory drugs. Research trends highlight its application in the synthesis of new derivatives with enhanced biological activity. Additionally, there is ongoing exploration of its environmental and safety profiles to support sustainable chemical production.

How should waste containing 4-amino-2-hydroxybenzoic acid, pyridine-4-carbohydrazide (CAS: 2066-89-9) be handled?

Waste containing 4-amino-2-hydroxybenzoic acid, pyridine-4-carbohydrazide (CAS: 2066-89-9) should be collected in appropriate containment to prevent environmental contamination. It is recommended to neutralize the waste before disposal to mitigate potential acid or base hazards. Incineration is a common method for disposal, provided it is conducted in an industrial incinerator with proper pollution control measures. Alternatively, professional waste disposal services can ensure compliance with local and international regulations for safe waste management.