Boc-NH-PEG7-acid

Basic Information

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CAS Number

2055044-68-1

Molecular Formula

C22H43NO11

Molecular Weight

497.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

SMILES

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O=C(OC(C)(C)C)NCCOCCOCCOCCOCCOCCOCCOCCC(O)=O

InChI

InChI=1S/C22H43NO11/c1-22(2,3)34-21(26)23-5-7-28-9-11-30-13-15-32-17-19-33-18-16-31-14-12-29-10-8-27-6-4-20(24)25/h4-19H2,1-3H3,(H,23,26)(H,24,25)

InChIKey

NRLJITQFPLHTDR-UHFFFAOYSA-N

LogP

1.102000000000004

Topological Polar Surface Area

140.24000000000004 Å²

Hydrogen Bond Donor/Acceptor

2 / 12

Complexity

486

Synonyms & References

English

t-Boc-N-amido-PEG7-acid
BocNH-PEG7-CH2CH2COOH
Boc-NH-PEG7-acid
Boc-NH-PEG7-CH2CH2COOH
t-boc-N-amido-PEG7-propionic acid

MDL Number

MFCD29052162

FAQ

What are the physical and chemical properties of Boc-NH-PEG7-acid (CAS: 2055044-68-1)?

Boc-NH-PEG7-acid (CAS: 2055044-68-1) is a polyethylene glycol derivative with a molecular weight around 1221 Da. It is a white or off-white solid with a crystalline form. This compound has low solubility in water but is soluble in organic solvents. It is reactive towards carboxylic acids and amine groups, making it useful in conjugation reactions. Its physical properties include a melting point of approximately 150-160°C and a density of about 1.1 g/cm³.

How is Boc-NH-PEG7-acid (CAS: 2055044-68-1) typically synthesized?

Boc-NH-PEG7-acid is typically synthesized by reacting Boc-amine with polyethylene glycol (PEG) of 7,000 molecular weight in the presence of a coupling agent such as 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) and N-hydroxysuccinimide (NHS). The reaction occurs under anhydrous conditions and is optimized for high yield. The product is purified by precipitation from organic solvents and drying.

What industries use Boc-NH-PEG7-acid (CAS: 2055044-68-1)?

Boc-NH-PEG7-acid (CAS: 2055044-68-1) is widely used in pharmaceuticals for conjugating proteins and peptides, in polymer science for creating polymeric materials, in sensor technology for biosensing applications, and in the semiconductor industry for manufacturing processes. It is also applied in the development of drug delivery systems and in academic research for various chemical and biological studies.

What precautions should be taken when handling Boc-NH-PEG7-acid (CAS: 2055044-68-1)?

When handling Boc-NH-PEG7-acid (CAS: 2055044-68-1), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Operations should be performed in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately with appropriate absorbent materials. Always refer to the safety data sheet (SDS) for detailed handling and disposal information and ensure that all waste is disposed of according to local regulations.