(1R)-1-[6-(4-Fluoro-1H-pyrazol-1-yl)-3-pyridinyl]ethanamine | CAS No. 2054317-97-2

(1R)-1-[6-(4-Fluoro-1H-pyrazol-1-yl)-3-pyridinyl]ethanamine

Basic Information

CAS Number

2054317-97-2

Molecular Formula

C10H11FN4

Molecular Weight

206.22 g/mol

AD

Basic Physical Properties

FC1=CN(C2=CC=C([C@H](N)C)C=N2)N=C1

InChI

InChI=1S/C10H11FN4/c1-7(12)8-2-3-10(13-4-8)15-6-9(11)5-14-15/h2-7H,12H2,1H3/t7-/m1/s1

InChIKey

VOWGRXGCGYJWNO-SSDOTTSWSA-N

LogP

1.4261000000000001

Topological Polar Surface Area

56.730000000000004 Ų

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

214

Synonyms & References

English

  • (S)-1-(6-(4-Fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethanamine
  • (R)-1-(6-(4-Fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethan-1-amine
  • (S)-1-[6-(4-Fluoro-1-pyrazolyl)-3-pyridyl]ethanamine
  • SY266031
  • 1-(6-(4-Fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethan-1-amine

FAQ

What are the physical and chemical properties of (1R)-1-[6-(4-Fluoro-1H-pyrazol-1-yl)-3-pyridinyl]ethanamine (CAS: 2054317-97-2)?

(1R)-1-[6-(4-Fluoro-1H-pyrazol-1-yl)-3-pyridinyl]ethanamine is a crystalline compound with a molecular weight of approximately 273.24 g/mol. It has a solubility of about 0.014 g/100 mL in water. The compound is reactive and can participate in nucleophilic substitution reactions. It is stable under normal conditions but should be stored in a dry, cool place away from direct sunlight.

How is (1R)-1-[6-(4-Fluoro-1H-pyrazol-1-yl)-3-pyridinyl]ethanamine (CAS: 2054317-97-2) typically synthesized?

(1R)-1-[6-(4-Fluoro-1H-pyrazol-1-yl)-3-pyridinyl]ethanamine can be synthesized through a multi-step process involving the reaction of 4-fluoro-1H-pyrazole and 3-pyridinecarbaldehyde. The synthesis typically uses a palladium catalyst and requires careful control of reaction conditions to achieve high yields and selectivity. The process is documented in various academic publications and patents.

What industries use (1R)-1-[6-(4-Fluoro-1H-pyrazol-1-yl)-3-pyridinyl]ethanamine (CAS: 2054317-97-2)?

(1R)-1-[6-(4-Fluoro-1H-pyrazol-1-yl)-3-pyridinyl]ethanamine is primarily used in the pharmaceutical industry as an intermediate in drug synthesis. It also finds applications in the development of new materials, particularly in the areas of polymers and sensors. The compound's unique chemical properties make it valuable for various research and development activities in these fields.

What precautions should be taken when handling (1R)-1-[6-(4-Fluoro-1H-pyrazol-1-yl)-3-pyridinyl]ethanamine (CAS: 2054317-97-2)?

When handling (1R)-1-[6-(4-Fluoro-1H-pyrazol-1-yl)-3-pyridinyl]ethanamine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbents. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.

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