7-(dimethoxymethyl)-1,2,3,4-tetrahydro-1,8-naphthyridine

Basic Information

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CAS Number

204452-91-5

Molecular Formula

C11H16N2O2

Molecular Weight

208.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

91-92.5 ºC

Boiling Point

311℃ at 760 mmHg

Flash Point

141.9°C

Refractive Index

1.523

SMILES

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COC(C1=NC2=C(CCCN2)C=C1)OC

InChI

InChI=1S/C11H16N2O2/c1-14-11(15-2)9-6-5-8-4-3-7-12-10(8)13-9/h5-6,11H,3-4,7H2,1-2H3,(H,12,13)

InChIKey

KKTPPUNNCIHOFA-UHFFFAOYSA-N

LogP

1.7310999999999999

Topological Polar Surface Area

43.38 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

197

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

1,8-Naphthyridine, 7-(dimethoxymethyl)-1,2,3,4-tetrahydro-
7-dimethoxymethyl-1,2,3,4-tetrahydro-1,8-naphthyridine
7-Dimethoxymethyl-1,2,3,4-tetrahydro-[1,8]naphthyridine, AldrichCPR
2-Dimethoxymethyl-5,6,7,8-tetrahydro-[1,8]naphthyridine
MFCD06657573
KKTPPUNNCIHOFA-UHFFFAOYSA-N
1,8-Naphthyridine,7-(dimethoxymethyl)-1,2,3,4-tetrahydro-
7-(Dimethoxymethyl)-1,2,3,4-tetrahydro-1,8-naphthyridine
DS-17034
AMY38816
A814568
DTXSID70590322
2-(dimethoxymethyl)-5,6,7,8-tetrahydro-1,8-naphthyridine
CS-W005282
AKOS015851632
7-(Dimethoxymethyl)-1 pound not2 pound not3 pound not4-tetrahydro-1 pound not8-naphthyridine
Dimethoxy-1,2,3,4-tetrahydropyridino[2,3-b]pyridin-7-ylmethane
7-Dimethoxymethyl-1,2,3,4-tetrahydro-[1,8]naphthyridine
FT-0677578
AB25608
204452-91-5
SCHEMBL325378
7-DIMETHOXYMETHYL-1,2,3,4-TETRAHYDRO-[1,8]NAPHTHYRIDINE
0495AB
AX8027978
ST2406537
D57018
7-dimethoxymethyl-1,2,3,4-te

MDL Number

MFCD06657573

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 7-(dimethoxymethyl)-1,2,3,4-tetrahydro-1,8-naphthyridine (CAS: 204452-91-5)?

7-(Dimethoxymethyl)-1,2,3,4-tetrahydro-1,8-naphthyridine is a crystalline solid with a molecular weight of approximately 231.25 g/mol. It has a solubility of about 10 mg/mL in water and is slightly soluble in common organic solvents like ethanol and acetone. The compound is stable under normal conditions but can react with strong acids and bases. It is also susceptible to moisture, and air oxidation may occur, leading to color changes.

How is 7-(dimethoxymethyl)-1,2,3,4-tetrahydro-1,8-naphthyridine (CAS: 204452-91-5) typically synthesized?

7-(Dimethoxymethyl)-1,2,3,4-tetrahydro-1,8-naphthyridine is typically synthesized via a multistep process involving the condensation of 1,8-naphthyridine with dimethylmethoxyamine. The reaction is usually carried out in the presence of a catalyst such as pyridine. The overall yield is around 70-80%, and the product can be purified by recrystallization from ethanol.

What industries use 7-(dimethoxymethyl)-1,2,3,4-tetrahydro-1,8-naphthyridine (CAS: 204452-91-5)?

7-(Dimethoxymethyl)-1,2,3,4-tetrahydro-1,8-naphthyridine is used in pharmaceutical and chemical industries for the development of novel drugs and as a precursor in the synthesis of other chemical compounds. It is also utilized in the polymer and sensor industries due to its functional groups and electronic properties.

What precautions should be taken when handling 7-(dimethoxymethyl)-1,2,3,4-tetrahydro-1,8-naphthyridine (CAS: 204452-91-5)?

When handling 7-(dimethoxymethyl)-1,2,3,4-tetrahydro-1,8-naphthyridine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from strong acids and bases. If a spill occurs, it should be carefully cleaned up using appropriate procedures. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.