(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(4-(tert-butoxy)phenyl)butanoic acid | CAS No. 204384-69-0

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(4-(tert-butoxy)phenyl)butanoic acid

Basic Information

CAS Number

204384-69-0

Molecular Formula

C29H31NO5

Molecular Weight

473.57 g/mol

AD

Basic Physical Properties

CC(C)(C)OC1=CC=C(C=C1)CCC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

InChI

InChI=1S/C29H31NO5/c1-29(2,3)35-20-15-12-19(13-16-20)14-17-26(27(31)32)30-28(33)34-18-25-23-10-6-4-8-21(23)22-9-5-7-11-24(22)25/h4-13,15-16,25-26H,14,17-18H2,1-3H3,(H,30,33)(H,31,32)/t26-/m0/s1

InChIKey

FKUBPXDMQFEPGP-SANMLTNESA-N

LogP

5.788400000000006

Topological Polar Surface Area

84.86 Ų

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

688

Synonyms & References

English

  • Benzenebutanoic acid, 4-(1,1-dimethylethoxy)-alpha-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (alphaS)-
  • 204384-69-0
  • N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-t-butyl-L-homotyrosine (Fmoc-L-hTyr(tBu)-OH)
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-[4-[(2-methylpropan-2-yl)oxy]phenyl]butanoic acid
  • Fmoc-HoTyr-OH.DCHA
  • MFCD01321420
  • CS-0087329
  • Fmoc-L-HTyr(tBu)-OH
  • Fmoc-L-homoTyr(tBu)-OH
  • Fmoc-beta-Homo-Phe-OH
  • (S)-2-(Fmoc-amino)-4-(4-tert-butoxyphenyl)butanoic acid
  • BS-16526
  • AKOS027251140
  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(4-(tert-butoxy)phenyl)butanoic acid
  • Benzenebutanoic acid,4-(1,1-dimethylethoxy)-a-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (aS)-
  • Benzenebutanoicacid, 4-(1,1-dimethylethoxy)-a-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (S)-
  • Fmoc-HoMoPhe-OH
  • FMOC-L-HOMOPHENYL-ALA

MDL Number

MFCD01321420

FAQ

What are the physical and chemical properties of (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(4-(tert-butoxy)phenyl)butanoic acid (CAS: 204384-69-0)?

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(4-(tert-butoxy)phenyl)butanoic acid is a white crystalline solid with a molecular weight of approximately 604.5 g/mol. It is poorly soluble in water but soluble in organic solvents like dichloromethane and ethanol. Chemically, it is known for its stability and limited reactivity, making it suitable for various chemical modifications. Its crystalline form facilitates ease of handling and storage.

How is (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(4-(tert-butoxy)phenyl)butanoic acid (CAS: 204384-69-0) typically synthesized?

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(4-(tert-butoxy)phenyl)butanoic acid is synthesized through a multi-step process involving the coupling of a fluorenylmethoxycarbonyl (Fmoc) protected amino acid with a tert-butoxy substituted aromatic compound. The synthesis typically involves the use of coupling reagents like HATU or DCM/DMAP, yielding a final product with high selectivity and good yield under optimized conditions.

What industries use (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(4-(tert-butoxy)phenyl)butanoic acid (CAS: 204384-69-0)?

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(4-(tert-butoxy)phenyl)butanoic acid is used in the pharmaceutical industry for the synthesis of medicinal compounds. It also finds applications in polymer science, where it serves as a functional monomer. Additionally, it plays a role in the development of sensors and semiconductors, particularly in the modification of surfaces and in the preparation of functional materials.

What precautions should be taken when handling (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(4-(tert-butoxy)phenyl)butanoic acid (CAS: 204384-69-0)?

When handling (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(4-(tert-butoxy)phenyl)butanoic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be used in a well-ventilated environment or within a fume hood to avoid inhalation. Spills should be handled according to the safety data sheet (SDS) guidelines, which typically involve the use of absorbent materials and proper disposal methods. Always refer to the latest SDS for detailed handling and emergency procedures.

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