1-Chloro-3-fluoro-5-methoxybenzene

Basic Information

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CAS Number

202925-08-4

Molecular Formula

C7H6ClFO

Molecular Weight

160.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

18°C

Boiling Point

189 °C

Refractive Index

n20/D 1.511(lit.)

SMILES

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COC1=CC(=CC(=C1)Cl)F

InChI

InChI=1S/C7H6ClFO/c1-10-7-3-5(8)2-6(9)4-7/h2-4H,1H3

InChIKey

XPZBNEWAZPZUHF-UHFFFAOYSA-N

LogP

2.4877000000000002

Topological Polar Surface Area

9.23 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

110

Safety Information

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Hazard Statement

H227 Combustible liquid
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

AKOS015913929
FT-0643894
3-Chloro-5-fluoroanisole
H10446
C2218
3-Chloro-5-fluoroanisole, 97%
1-chloro-3-fluoro-5-methoxybenzene
A814403
AM82872
DTXSID10381352
GS-6411
SCHEMBL1477524
NS00126690
Benzene, 1-chloro-3-fluoro-5-methoxy-
1-CHLORO-3-FLUORO-5-METHOXY-BENZENE
SY050856
XPZBNEWAZPZUHF-UHFFFAOYSA-N
MFCD00070770
EN300-7254975
J-013188
202925-08-4
CS-0150470
1-Chloro-3-fluoro-5-methoxybenzene
Benzene,1-chloro-3-fluoro-5-methoxy-
3-chloro-5-fluoroanisol
3-fluoro-5-methoxy-1-chlorobenzene
PubChem2661
SBB087479
AS02725
VZ26667
AS04169

MDL Number

MFCD00070770

Customs Code

2909309090

FAQ

What regulatory guidelines apply to 1-Chloro-3-fluoro-5-methoxybenzene (CAS: 202925-08-4)?

1-Chloro-3-fluoro-5-methoxybenzene (CAS: 202925-08-4) is classified as a hazardous chemical under the Globally Harmonized System of Classification and Labeling of Chemicals (GHS), requiring proper safety data sheets (SDS) and appropriate hazard communication labels. For manufacturing and importing in the European Union, it falls under the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) regulation. Additionally, the U.S. Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA) have specific guidelines for handling and disposal, including reporting requirements for significant releases and disposal methods.

Are there alternatives to 1-Chloro-3-fluoro-5-methoxybenzene (CAS: 202925-08-4) in synthesis?

1-Chloro-3-fluoro-5-methoxybenzene (CAS: 202925-08-4) can be synthesized using various reagents. Alternatives include 1-bromo-3-fluoro-5-methoxybenzene and 1-iodo-3-fluoro-5-methoxybenzene, which can be used in similar synthetic routes. Additionally, other fluoro and chloro derivatives, such as 1-chloro-3,5-dimethoxybenzene and 1-chloro-3-fluorobenzene, can serve as useful intermediates in related chemical syntheses.

What is the market or research trend for 1-Chloro-3-fluoro-5-methoxybenzene (CAS: 202925-08-4)?

The market for 1-Chloro-3-fluoro-5-methoxybenzene (CAS: 202925-08-4) is driven by its use in pharmaceutical and agrochemical industries as an intermediate. Recent research trends focus on its applications in drug discovery and development, particularly in anti-inflammatory and analgesic compounds. Market trends indicate increasing demand due to the growing pharmaceutical sector and ongoing research into new drug candidates.

How should waste containing 1-Chloro-3-fluoro-5-methoxybenzene (CAS: 202925-08-4) be handled?

Waste containing 1-Chloro-3-fluoro-5-methoxybenzene (CAS: 202925-08-4) should be managed according to local and international regulations. Collect waste in appropriate containers and ensure proper labeling. Incineration is a common method for disposal, but it must be performed under controlled conditions to minimize environmental impact. Alternatively, professional waste disposal services can be utilized to ensure safe and compliant disposal. Always adhere to safety guidelines and consult local regulations for specific handling procedures.