Calcium dobesilate

Basic Information

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CAS Number

20123-80-2

Molecular Formula

C12H10CaO10S2

Molecular Weight

418.41 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

>300° (dec)

Solubility

H2O: soluble15mg/mL, clear

SMILES

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Oc1ccc(c(c1)S(=O)(=O)[O-])O.Oc1ccc(c(c1)S(=O)(=O)[O-])O.[Ca+2]

InChI

InChI=1S/C6H6O5S.Ca/c7-4-1-2-5(8)6(3-4)12(9,10)11;/h1-3,7-8H,(H,9,10,11);/q;+2/p-1

InChIKey

CKWYTUQEIPJUOD-UHFFFAOYSA-M

LogP

2.16540

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Toxicity

LD50 in mice: 700 mg/kg (Esteve-Subirana)

Synonyms & References

English

Calcium Dobesilate
Calcium Dobesilate Mnohydrate
Calcium bis(2,5-dihydroxybenzenesulfonate)
Calcium Dobesilate Monohydrate
calcium,2,5-dihydroxybenzenesulfonate
2,5-dihydroxybenzenesulfonic acid calcium salt
2,5-Dihydroxybenzenesulfonic acid calcium salt,205E,Calcium 2,5-dihydroxybenzenesulfonate
Calcii dobesilas
calcium 2,5-dihydroxy-phenylsulfonate
calcium salt of 2,5-dihydroxybenzenesulfonic acid
Dexium
Dobesilat-Calciumsalz
Dobesilate calcium
Dobesilato calcico
Doxium
Nugatex
Rasexinium
Toraxine
Calcium dobesilate
(2,5-dihydroxybenzenesulfonate)
calcium salt (2:1)

MDL Number

MFCD08457542

Customs Code

2924299090

FAQ

What is Calcium dobesilate (CAS: 20123-80-2)?

Calcium dobesilate (CAS: 20123-80-2) is a calcium salt of dobesilate, a sulfonamide compound with the chemical formula C15H14CaN2O6S2. It is a white crystalline powder, insoluble in water, and used primarily as an anticoagulant in pharmaceutical applications. Its structure and properties make it effective in preventing blood clot formation.

What are the main uses of Calcium dobesilate (CAS: 20123-80-2)?

Calcium dobesilate (CAS: 20123-80-2) is mainly used as an antithrombotic agent to treat conditions like deep vein thrombosis and peripheral artery disease. It is also employed in veterinary medicine for anticoagulant therapy. Additionally, it serves as a research compound for studying blood coagulation mechanisms and has industrial applications in specialty chemical formulations.

Is Calcium dobesilate (CAS: 20123-80-2) safe?

Calcium dobesilate (CAS: 20123-80-2) is generally considered safe when used as directed in medical and veterinary contexts. It has low toxicity and is well-tolerated, though rare side effects like gastrointestinal discomfort or allergic reactions may occur. Safety standards ensure its compliance with regulatory guidelines for pharmaceutical use, emphasizing proper handling and dosage.

How should Calcium dobesilate (CAS: 20123-80-2) be stored?

Calcium dobesilate (CAS: 20123-80-2) should be stored in a cool, dry place (20-25°C), protected from moisture and light. Keep in a sealed, airtight container to maintain stability. Avoid exposure to heat or direct sunlight, and store out of reach of children to ensure proper preservation and safety.