N~2~-[(Benzyloxy)carbonyl]-N~5~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine | CAS No. 201048-68-2

N~2~-[(Benzyloxy)carbonyl]-N~5~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine

Basic Information

CAS Number

201048-68-2

Molecular Formula

C28H28N2O6

Molecular Weight

488.54 g/mol

AD

Basic Physical Properties

OC(=O)[C@H](CCCNC(=O)OCC1C2=CC=CC=C2C2=C1C=CC=C2)NC(=O)OCC1=CC=CC=C1

InChI

InChI=1S/C28H28N2O6/c31-26(32)25(30-28(34)35-17-19-9-2-1-3-10-19)15-8-16-29-27(33)36-18-24-22-13-6-4-11-20(22)21-12-5-7-14-23(21)24/h1-7,9-14,24-25H,8,15-18H2,(H,29,33)(H,30,34)(H,31,32)/t25-/m0/s1

InChIKey

JEFQVIBFPUQDGA-VWLOTQADSA-N

LogP

4.684900000000003

Topological Polar Surface Area

113.96000000000002 Ų

Hydrogen Bond Donor/Acceptor

3 / 8

Synonyms & References

English

  • (S)-5-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(((benzyloxy)carbonyl)amino)pentanoic acid
  • (2S)-5-(9H-fluoren-9-ylmethoxycarbonylamino)-2-(phenylmethoxycarbonylamino)pentanoic acid
  • NA-Z-ND-FMOC-L-ORNITHINE
  • Nα-Z-Nδ-Fmoc-L-ornithine
  • Z-Orn(fmoc)-oh
  • Cbz-Orn(Fmoc)-OH
  • Nalpha-Z-Ndelta-Fmoc-L-ornithine
  • N5-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N2-[(phenylmethoxy)carbonyl]-L-ornithine

MDL Number

MFCD00237358

FAQ

What are the physical and chemical properties of N~2~-[(Benzyloxy)carbonyl]-N~5~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine (CAS: 201048-68-2)?

N~2~-[(Benzyloxy)carbonyl]-N~5~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine is a white crystalline compound with a molecular weight of approximately 728.9 g/mol. It has low water solubility but good solubility in organic solvents. Physically, it is heat-stable and exhibits limited reactivity under normal conditions. It is typically used in pharmaceutical applications where its stability and reactivity are beneficial.

How is N~2~-[(Benzyloxy)carbonyl]-N~5~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine (CAS: 201048-68-2) typically synthesized?

N~2~-[(Benzyloxy)carbonyl]-N~5~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine is typically synthesized through multi-step reactions involving protection and deprotection steps. Commonly, it is prepared from ornithine, followed by the introduction of the benzyloxycarbonyl and fluorenylmethoxycarbonyl groups using appropriate reagents and conditions. The synthesis involves the use of anhydrous conditions and specific catalysts to achieve high selectivity and yield.

What industries use N~2~-[(Benzyloxy)carbonyl]-N~5~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine (CAS: 201048-68-2)?

N~2~-[(Benzyloxy)carbonyl]-N~5~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine is primarily used in the pharmaceutical industry for the development of therapeutic agents. It is also utilized in research and development contexts for its unique chemical properties, making it suitable for applications in drug discovery, biotechnology, and materials science.

What precautions should be taken when handling N~2~-[(Benzyloxy)carbonyl]-N~5~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine (CAS: 201048-68-2)?

When handling N~2~-[(Benzyloxy)carbonyl]-N~5~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine, it is important to use appropriate personal protective equipment (PPE) such as gloves and eye protection. Store in a cool, dry place away from direct sunlight. Work in a well-ventilated area or fume hood to minimize inhalation risk. In case of spill, consult a material safety data sheet (MSDS) for specific instructions on clean-up procedures and disposal. Ensure all precautions are followed to maintain safety in the laboratory environment.

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