Flumethasone 21-Pivalate

Basic Information

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CAS Number

2002-29-1

Molecular Formula

C27H36F2O6

Molecular Weight

494.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Solubility

dioxane: soluble4.0ML, clear, colorless to very faintly yellow (50 mg + 4.0 mL dioxane)

SMILES

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CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COC(=O)C(C)(C)C)O)C)O)F)C)F

InChI

InChI=1S/C27H36F2O6/c1-14-9-16-17-11-19(28)18-10-15(30)7-8-24(18,5)26(17,29)20(31)12-25(16,6)27(14,34)21(32)13-35-22(33)23(2,3)4/h7-8,10,14,16-17,19-20,31,34H,9,11-13H2,1-6H3/t14-,16+,17+,19+,20+,24+,25+,26+,27+/m1/s1

InChIKey

JWRMHDSINXPDHB-OJAGFMMFSA-N

LogP

3.4407000000000023

Topological Polar Surface Area

100.9 Å²

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

1030

Synonyms & References

English

UNII-0DV09X6F21
6alpha,9alpha-Difluoro-16alpha-methylprednisolone 21-pivalate
NSC 107680
Q20817117
6.Alpha.,9-Difluoro-11.beta.,17,21-trihydroxy-16.alpha.-methylpregna-1,4-diene-3,20-dione 21-pivalate
[2-[(6S, 8S, 9R, 10S, 11S, 13S, 14S, 16R, 17R)-6, 9-difluoro-11, 17-dihydroxy-10, 13, 16-trimethyl-3-oxo-6, 7, 8, 11, 12, 14, 15, 16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2, 2-dimethylpropanoate
SCHEMBL6968
NCGC00022408-03
[2-[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate
FLUMETHASONE PIVALATE [USP IMPURITY]
6alpha,9-Difluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate
Locorten (TN)
Flumethasone 21-pivalate; Flumethasone pivalate; Locacorten; Locorten; Lorinden; Losalen
Flumethasone pivalate, United States Pharmacopeia (USP) Reference Standard
2-((6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl pivalate
CHEBI:31620
Flumethasone pivalate [USAN:USP]
Flumetasone 21-pivalate
Flumethasone pivalate, British Pharmacopoeia (BP) Reference Standard
Flumethsone pivalate
HY-107949
HMS3715L14
FLUMETASONE PIVALATE (EP MONOGRAPH)
2002-29-1
Flumethasone pivalate, European Pharmacopoeia (EP) Reference Standard
6alpha,9alpha-Difluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione, 21-pivalate
6alpha,9-difluoro-11beta,17-dihydroxy-16alpha-methyl-3,20-dioxopregna-1,4-dien-21-yl 2,2-dimethylpropanoate
6,9-Difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl pivalate
DTXCID2028931
Flumetasone pivalate
NCGC00022408-04

MDL Number

MFCD02380115

FAQ

What regulatory guidelines apply to Flumethasone 21-Pivalate (CAS: 2002-29-1)?

Flumethasone 21-Pivalate (CAS: 2002-29-1) is subject to various regulatory guidelines such as GHS classification for hazardous chemicals, REACH regulations in the EU, and FDA/EPA requirements in the United States. It is important to comply with these regulations for safe handling, storage, and disposal.

Are there alternatives to Flumethasone 21-Pivalate (CAS: 2002-29-1) in synthesis?

Alternatives to Flumethasone 21-Pivalate (CAS: 2002-29-1) in synthesis include other corticosteroids like dexamethasone or clobetasol. These compounds can be used as substitutes depending on the specific application and desired properties.

What is the market or research trend for Flumethasone 21-Pivalate (CAS: 2002-29-1)?

The market for Flumethasone 21-Pivalate (CAS: 2002-29-1) is focused on its use in topical dermatological treatments. Research trends are shifting towards understanding its efficacy and safety in various formulations and exploring its potential in new therapeutic areas.

How should waste containing Flumethasone 21-Pivalate (CAS: 2002-29-1) be handled?

Waste containing Flumethasone 21-Pivalate (CAS: 2002-29-1) should be collected in appropriate containers, labeled, and disposed of through professional waste disposal services. Environmental precautions include ensuring no contamination of soil or water sources during disposal.