2'-OMe-Ac-C Phosphoramidite

Basic Information

View in Editor

CAS Number

199593-09-4

Molecular Formula

C42H52N5O9P

Molecular Weight

801.9 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Insecticides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

View in Editor

CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OC)N2C=CC(=NC2=O)NC(=O)C)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

InChI

InChI=1S/C42H52N5O9P/c1-28(2)47(29(3)4)57(54-26-12-24-43)56-38-36(55-40(39(38)52-8)46-25-23-37(44-30(5)48)45-41(46)49)27-53-42(31-13-10-9-11-14-31,32-15-19-34(50-6)20-16-32)33-17-21-35(51-7)22-18-33/h9-11,13-23,25,28-29,36,38-40H,12,26-27H2,1-8H3,(H,44,45,48,49)/t36-,38-,39+,40-,57?/m1/s1

InChIKey

WNWUMIPFLOKTEZ-MNVCMFJRSA-N

LogP

6.87418

Complexity

1370

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

N-{1-[(2R,3S,4R,5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-({[bis(propan-2-yl)amino](2-cyanoethoxy)phosphanyl}oxy)-3-methoxyoxolan-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl}acetamide
N-[1-[(2R,3S,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
4-Acetamido-1-(5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-2-O-methyl-beta-D-arabinofuranosyl)pyrimidin-2(1H)-one
Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
(2R,3R,4R,5R)-5-(4-Acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
AKOS016003790
DMT-2'-O-methyl-rC(Ac) Phosphoramidite
N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
DTXSID80743382
199593-09-4
2'-OMe-Ac-CPhosphoramidite
N-Acetyl-5/'-O-(4,4-dimethoxytrityl)-2/'-O-methylcytidine-3/'-(2-cyanoethyl-N,N-diisopropyl)phosphor
N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methylcytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
5'-O-DMT-2'-O-Me-rC(N-Ac)-3'-CEDPA
2-Methyl-6-phenyl-3,7-dihydroimidazo[1,2-a]pyrazin-3(7H)-one
2'-O-Methyl-N4-Acetyl-5'-O-DMT-Cytidine-3'-CE-Phosphoramidite
DMT-2′O-Methyl-rC(ac) Phosphoramidite
N4-ACETYL-5'-O-DMT-2'-O-METHYLCYTIDINE 3'-CE PHOSPHORAMIDITE
N-acetyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-cytidine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
2’-O-Methyl-rC(N-Ac)Phosphoramidite
-5-(4-Acetamido-2-oxopyrimidin-1(2H)
5'-DMT-2'-OMe-rC(N-Ac) Phosphoramidite
2'-OMe-Ac-C Phosphoramidite
2'-OMe-Ac-C Phosphoramidite
Dmt-2'o-methyl-rc(ac) amidite
C42H52N5O9P
0262AB
6726AD
593D094
5'-O-(4,4'-

MDL Number

MFCD12912403

FAQ

What regulatory guidelines apply to 2'-OMe-Ac-C Phosphoramidite (CAS: 199593-09-4)?

2'-OMe-Ac-C Phosphoramidite (CAS: 199593-09-4) falls under various regulatory guidelines including GHS classification for hazardous chemicals, REACH regulations for European manufacturers and importers, and FDA/EPA requirements for safety and environmental protection. Specific handling, storage, and disposal instructions must be followed based on its classification as a hazardous substance.

Are there alternatives to 2'-OMe-Ac-C Phosphoramidite (CAS: 199593-09-4) in synthesis?

Several alternatives to 2'-OMe-Ac-C Phosphoramidite can be used in synthesis, including other phosphoramidites like 2'-fluoro-acetyl and 2'-methoxy-acetyl. These alternatives offer similar functionalities and can be chosen based on cost, availability, and specific application requirements.

What is the market or research trend for 2'-OMe-Ac-C Phosphoramidite (CAS: 199593-09-4)?

The market for 2'-OMe-Ac-C Phosphoramidite (CAS: 199593-09-4) is growing due to increasing demand in nucleic acid synthesis and oligonucleotide production. Research trends highlight its use in drug discovery and genetic engineering. Price trends indicate stability with minor fluctuations based on supply chain dynamics and global economic conditions.

How should waste containing 2'-OMe-Ac-C Phosphoramidite (CAS: 199593-09-4) be handled?

Waste containing 2'-OMe-Ac-C Phosphoramidite (CAS: 199593-09-4) should be collected in a sealed, labeled container and disposed of through professional waste disposal services. Incineration is a common method, and environmental precautions should be taken to prevent contamination of soil and water. Compliance with local regulations and guidelines is essential for safe disposal.