Atazanavir Impurity 19

Basic Information

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CAS Number

198904-85-7

Molecular Formula

C17H21N3O2

Molecular Weight

299.37 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

78-81°C

Refractive Index

1.55

SMILES

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CC(C)(C)OC(=O)NNCC1=CC=C(C=C1)C2=CC=CC=N2

InChI

InChI=1S/C17H21N3O2/c1-17(2,3)22-16(21)20-19-12-13-7-9-14(10-8-13)15-6-4-5-11-18-15/h4-11,19H,12H2,1-3H3,(H,20,21)

InChIKey

GIMJTKJSKPENNG-UHFFFAOYSA-N

LogP

3.2779000000000016

Topological Polar Surface Area

63.25 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

346

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Hydrazinecarboxylicacid,2-[[4-(2-pyridinyl)phenyl]methyl]-,1,1-dimethylethylester
198904-85-7
A51031
Hydrazinecarboxylic acid, 2-[[4-(2-pyridinyl)phenyl]methyl]-, 1,1-dimethylethyl ester
tert-butyl 2-(4-(pyridin-2-yl)benzyl)hydrazine-1-carboxylate
T-butyl-2-[4-(pyridin-2-yl)benzyl] hydrazine carboxylate
TERT-BUTYL2-(4-(PYRIDIN-2-YL)BENZYL)HYDRAZINECARBOXYLATE
AS-15477
CS-0141577
A4355
N'-{[4-(pyridin-2-yl)phenyl]methyl}(tert-butoxy)carbohydrazide
tert-butyl3-[4-(pyridin-2-yl)benzyl]carbazate
Tert-butyl N-[(4-pyridin-2-ylphenyl)methylamino]carbamate
TERT-BUTYL 2-(4-(PYRIDIN-2-YL)BENZYL)HYDRAZINECARBOXYLATE
AM84683
J-012848
MFCD04035550
tert-butyl 2-[4-(2-pyridinyl)benzyl]hydrazinecarboxylate
SCHEMBL6692
tert-Butyl 2-{[4-(pyridin-2-yl)phenyl]methyl}hydrazine-1-carboxylate
N'-(4-Pyridin-2-yl-benzyl)-hydrazinecarboxylic acid tert-butyl ester
AKOS015908769
1-Boc-2-[4-(2-pyridinyl)benzylidene]hydrazine
DTXSID40430867
BCP28313
GIMJTKJSKPENNG-UHFFFAOYSA-N
FT-0657986
tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate
N-1-(tert-butoxycarbonyl)-N-2-[4-(pyridin-2-yl)benzyl]hydrazine
T-butyl-2-[4-(pyridin-2-yl)benzyl] hydrazinecarboxylate
Hydrazinecarboxylic acid

MDL Number

MFCD09701469

FAQ

What is Atazanavir Impurity 19 (CAS: 198904-85-7)?

Atazanavir Impurity 19, with the CAS number 198904-85-7, is a known impurity associated with the antiretroviral drug atazanavir. It is typically identified during the synthesis or purification process of pharmaceutical compounds. The exact chemical structure and formula may vary depending on the source, but it is generally considered a minor byproduct that may affect the purity and quality of the final drug product.

What are the main uses of Atazanavir Impurity 19 (CAS: 198904-85-7)?

Atazanavir Impurity 19 is primarily used in the analysis and quality control of atazanavir-based pharmaceuticals. It helps in identifying potential contaminants during drug development and manufacturing. This impurity is also relevant in research settings for understanding degradation pathways and ensuring the safety and efficacy of the drug in clinical applications.

Is Atazanavir Impurity 19 (CAS: 198904-85-7) safe?

Atazanavir Impurity 19 is generally considered less hazardous than the parent drug, atazanavir, but it should still be handled with care. Safety guidelines recommend following standard laboratory practices to minimize exposure. Regulatory agencies typically set acceptable limits for this impurity in drug products to ensure patient safety and compliance with quality standards.

How should Atazanavir Impurity 19 (CAS: 198904-85-7) be stored?

Atazanavir Impurity 19 should be stored in a cool, dry, and dark place, ideally at temperatures below 25°C. It is recommended to keep it in a sealed container to prevent moisture and air exposure. Proper storage conditions help maintain its chemical stability and prevent unwanted reactions or degradation over time.