3-Fluorophenylalanine

Basic Information

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CAS Number

19883-77-3

Molecular Formula

C9H10FNO2

Molecular Weight

183.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

250-254°C

Boiling Point

305℃ at 760 mmHg

Density

1.293

Flash Point

138.3°C

Refractive Index

-6 ° (C=2, 1mol/L HCl)

Specific Rotation

-25 º (c=1% in H2O)

SMILES

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C1=CC(=CC(=C1)F)CC(C(=O)O)N

InChI

InChI=1S/C9H10FNO2/c10-7-3-1-2-6(4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)/t8-/m0/s1

InChIKey

VWHRYODZTDMVSS-QMMMGPOBSA-N

LogP

0.7801000000000002

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

187

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

AC-5827
m-Fluoro-L-phenylalanine
SCHEMBL42949
m-Fluoro-L-phenylalanine, >=99.0% (sum of enantiomers, HPLC)
Q27147557
DTXSID50941737
(s)-2-amino-3-(3-fluorophenyl)propanoic acid
(2S)-2-azanyl-3-(3-fluorophenyl)propanoic acid
F0272
3-Fluoro-L-phenylalanine
CHEMBL300672
m-Fl-phenylalanine
C9H10FNO2
FL-PHE
m-Fluoro-phenylalanine
AKOS012010904
(s)-2-amino-3-(3-fluoro-phenyl)-propionic acid
CHEBI:77957
19883-77-3
(2S)-2-amino-3-(3-fluorophenyl)propanoic acid
(S)-2-Amino-3-(3-fluorophenyl)propionic Acid
CS-0011429
h-m-fluoro-phe-oh
MFCD00066450
CS-12006
h-phe(3-f)-oh
L-Phenylalanine, 3-fluoro-
VWHRYODZTDMVSS-QMMMGPOBSA-N
A814034
EN300-317048
L-3-fluorophenylalanine

MDL Number

MFCD00066450

FAQ

What are the physical and chemical properties of 3-Fluorophenylalanine (CAS: 19883-77-3)?

3-Fluorophenylalanine (CAS: 19883-77-3) is a colorless solid with a molecular weight of approximately 175.07 g/mol. It has a solubility of about 6.8 mg/mL in water and is slightly soluble in ethanol. Chemically, it exhibits properties typical of an amine and an ester, making it reactive in both basic and acidic conditions.

How is 3-Fluorophenylalanine (CAS: 19883-77-3) typically synthesized?

3-Fluorophenylalanine is typically synthesized via protecting group strategies, such as introducing a leaving group like a chloromethyl or tosyl group onto benzene. Common methods involve the use of fluorination of benzyl or bromophenylalanine derivatives, followed by deprotection with acids or bases. Specific synthetic routes can vary based on the desired product and scale of production.

What industries use 3-Fluorophenylalanine (CAS: 19883-77-3)?

3-Fluorophenylalanine (CAS: 19883-77-3) finds applications in several industries. It is used in the pharmaceutical sector for the development of novel drugs and as a precursor in organic synthesis. It also has potential in the polymer industry for creating new materials with unique properties. Additionally, it is explored in the sensor and semiconductor industries for its electronic properties.

What precautions should be taken when handling 3-Fluorophenylalanine (CAS: 19883-77-3)?

When handling 3-Fluorophenylalanine (CAS: 19883-77-3), it is important to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and flammable materials. In case of a spill, use appropriate absorbent materials and dispose of them according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.